Livagen yog bioactive peptide hauv tsev neeg Khavinson; Qhov tshwj xeeb amino acid ib ntus yog Lys-Glu-Asp-Ala. Kev tshawb fawb txog kev tiv thaiv kev laus thiab kev ua neej ntev pib ua rau nws nrhiav tau.
Multidimensional, multi-targeted zog yog ib qho ntawm nws cov yam ntxwv tseem ceeb tshaj plaws. Mimicking endogenous signaling molecules, nws ncaj qha ua rau ob lub cell nucleus thiab mitochondria cov tsos mob; muaj zog gene txoj cai thiab kev tiv thaiv cellular yog qhov tshwm sim ua haujlwm.
Kev txhawb nqa ntawm histone (H5 thiab H2A tshwj xeeb) acetylation unwinds lub nruj coiled DNA qauv tsim nyog rau kom raug kev sau ntawv.
Cov noob muaj txiaj ntsig yav dhau los silenced lossis downregulated los ntawm cov txheej txheem kev laus yog reactivated kom rov qab cellular 'youthfulness’ transcriptional xeev.
Txhim kho telomerase kev ua si thiab qeeb telomere attrition thaum lub sij hawm faib yog lwm qhov tseem ceeb.
ATP synthesis yog txhim kho, lub zog metabolism thiab tag nrho qhov tseem ceeb yog cov khoom kawg.
Muaj hwj chim antioxidant kev ua si, neuroendocrine system cawv, Kev hloov pauv kev ntxhov siab thiab kev pw tsaug zog zoo yog txhua yam cuam tshuam zoo; homeostasis yog lub hom phiaj kawg ntawm Livagen qhov kev ua.
Ib ntus
H-Lys-Glu-Asp-Ala-OH
CAS Nr
/
Molecular Formula
C18H31N5O9
Molecular Luj
461.472
Kev tshawb fawb ntawm Livagen Peptide
1.Txoj Cai Epigenetic thiab tom qab Gene Expression
Kev tswj hwm Epigenetic yog lub hauv paus txheej txheem ntawm kev ua haujlwm rau tsev neeg ntawm peptides.
Acetylation ntawm histones (raws li tau hais los saum no) coj mus rau ib chromatin qauv hloov los ntawm heev condensed mus rau ib tug so euchromatic xeev.
RNA polymerase thiab cov ntsiab lus ntawm kev txhais lus, muaj peev xwm nkag tau’ yav tas los unengaged noob.
Kev sim tau pom ntau cov noob muaj txiaj ntsig ua tsis muaj zog hauv cov hnub nyoog laus los ntawm histone deacetylation.
Livagen thim rov qab cov txheej txheem no, rov teeb tsa cov kev pab cuam transcriptional, yog qhov txhais tau tias nws muaj peev xwm tiv thaiv kev laus.
2.Telomere Kev tu
Shortening ntawm telomeres yog ib qho cim ntawm cellular aging.
Cell faib nws tus kheej ua rau qhov no attrition, nrog apoptosis yog qhov kawg taw tes yog tias telomeres ncav cuag lub xeev luv luv.
Livagen ncua qhov no, thiab xws li khaws cia lossis ncua lub neej ntawm cov cell thiab cov ntaub so ntswg.
3.Txhim kho Mitochondrial Muaj nuj nqi thiab Bioenergetics
Livagen haib optimizes mitochondrial zog ntau lawm.
Txhim khu kev ua haujlwm ntawm mitochondrial electron thauj saw yog lub hauv paus ntawm txoj kev no, nrog adenosine triphosphate (ATP) synthesis yog ib tug ncaj qha tshwm sim.
Tom qab ntawd muaj ntau lub zog cellular muaj; lub cev lub zog tag nrho cov qauv yog txhim kho, lub cev tseem ceeb heev tom qab los ntawm lub xeev no.
Qhov tseem ceeb ntawm kev tawm tsam ntau dhau, stress-induced zus tau tej cov reactive oxygen hom ua tiav – endogenous momentum ntawm kev tswj cov tub ntxhais hluas tseem ceeb yog qhov kawg point ntawm no mechanism.
4.Antioxidant thiab Anti-inflammatory teebmeem
Livagen upregulates ntau yam antioxidant active tshuaj; hloov cov kab mob oxidative puas tsuaj rau hauv cov tshuaj tsis muaj teeb meem yog nws qhov haujlwm tseem ceeb.
Endogenous self-production yog qhov tseeb qhov zoo ntawm no, exogenous antioxidants tau outperformed nyob rau hauv txhua yam (efficiency, kev nyob ruaj khov, systemic ncav cuag).
Cell membranes, cov proteins, lipids thiab DNA, tau txais kev dav, Lub sij hawm ntev tiv thaiv los ntawm txhua hom kev ntxhov siab oxidative.
Kev puas tsuaj ntawm molecular yog txo los ntawm cov txheej txheem no.
COA
HPLC
MS
