Acetyl Tetrapeptide-3 ndi yopangidwa biomimetic peptide wopangidwa ndi zotsalira zinayi za amino acid.
M'zaka zaposachedwa yapeza chidwi chachikulu monga chogwiritsira ntchito mu cosmetology ndi dermatology; mankhwala omwe amalimbikitsa kukula kwa tsitsi ndikuthandizira kutayika tsitsi kukhala zitsanzo zabwino kwambiri.
Kutsatizana
Ac-Lys-Gly-Malemba-Ake
Nambala ya CAS
827306-88-7
Molecular Formula
C22H38N8O6
Kulemera kwa Maselo
510.61 g/mol
Kafukufuku Wa Acetyl Tetrapeptide-3
Njira yayikulu yogwirira ntchito ya peptide iyi ndikulimbikitsa mwachindunji kapena mwanjira ina yolimbikitsa ma dermal fibroblasts ndipo dermal papilla cell (Zithunzi za DPC) kupanga ndi kubisa kiyi Mtundu III wa collagen.
Collagen wamtundu wa III ndiwofunikira kwambiri pakhungu, minyewa yolumikizana makamaka yozungulira tsitsi – Thandizo losinthika lokhazikika ndilo ntchito yoyamba yomwe imachokera.
Kutsatira chithandizo ndi Acetyl Tetrapeptide-3, kusanthula kuchuluka kwawonetsa a +65% kuwonjezeka kwa mtundu wa III collagen expression, lamini kukhala chikhomo china chotsatiridwa bwino (+285% wonjezani).
Lembani VII collagen amapanga ulusi woyambira wokhazikika, kulumikiza mwamphamvu nembanemba yapansi ku dermis pansipa.
Kafukufuku wawonetsa kuti Acetyl Tetrapeptide-3 yobwezeretsanso kutsika kwa cortisol mu mtundu wa collagen uwu., potero kukonza ndi kulimbikitsa chigawo cha dermal-epidermal (MADZI) kapangidwe.
Acetyl Tetrapeptide-3 imapangitsa kuti tsitsi likhale lomatira kumutu, komanso kulimbikitsa chitukuko chatsopano cha follicle.
Maphunziro a in vitro ndi ex vivo atsimikizira mokwanira njira yomwe tatchulayi.
Nanoliposomes zopangidwa ndi peptides yamkuwa, Acetyl Tetrapeptide-3 ndi myristoyl pentapeptide-4 zatsimikiziridwa kuti zimalimbikitsa kukula kwa tsitsi kudzera m'njira zonse pamwambapa..
Kuchita bwino kwachipatala kwakhazikitsidwa.
A 24-sabata, mosasintha, kuyesedwa koyang'aniridwa ndi akhungu patatu poyerekeza ndi mapangidwe azitsamba (yomwe ili ndi Acetyl Tetrapeptide-3 monga gawo la zinthu zomwe zimagwira ntchito) ku 3% minoxidil, ndikuwonetsa mphamvu zofananira pochiza androgenetic alopecia ndi mbiri yabwino yachitetezo.
COA
Mtengo wa HPLC
MS
