Crystagen yakakosha bio-regulatory peptide yakagadzirirwa kusimudzira simba remuviri rekudzivirira masimba.. Kuongorora kwakarongeka kwe thymus basa uye zvinhu zvaro zvepachivande zvakakonzera kuumbwa kwayo kuburikidza nekugadzira nemaune.
Kubva kuwanikwa, multi-level, Multi-target biological regulatory kugona kwakaratidzwa kune Crystagen. Iko core efficacy iri mukunyanya uye kunyatso kuvandudza zvakasiyana-siyana zve immune system basa.
Immunomodulatory simba rinobva zvakananga kubva kune yakanaka regulation ye chaiyo T lymphocyte subsets – mubatsiri Th masero kuva muenzaniso mukuru, pamwe na cytotoxic T masero; kukurudzira kwavo kuwanda, activation, uye secretion yakatevera ye effector mamorekuru ari pakati pekuita uku.
B-sero yakabatana activation uye humoral immunity zvakare modulated, synergistically kupedzisa mhinduro yezvirwere zvemuviri.
Kutevedzera endo native immune signing mamorekuru pachayo ndeimwe yenzira dzakakosha dzeCrystagen; ligand-Kupindirana kwemhando yekugamuchira pamusoro pemasero ekudzivirira muviri kunotanga nzira dzemukati.
Zvimwe zvidzidzo zvekiriniki zvakashuma zvakananga anti-inflammatory effect, kuderedza maitiro akasiyana-siyana ekudzivirira kusagadzikana kunokanganisa muviri.
Normalization ye microenvironmental states inzvimbo inodiwa yekupedzisira.
Yakasimba immunomodulation (zvazvino uye zveramangwana) ndizvo zvinovavarirwa neCrystal kuzadzisa.
Kutevedzana
Glu-Asp-Pro
Nhamba yeCAS
/
Molecular Formula
C14H21N3O8
Molecular Weight
359.335
Tsvakurudzo yeCrystagen Peptide
1.Regulating lymphocytes
Direct action on cellular immune mhinduro ndiyo inonyanya kutariswa neCrystal.
Faster, kuwedzera kunoshanda uye huwandu hwakazara hwekusiyanisa kwakakodzera mukuita basa rekuita T masero pamusoro antigen kusangana zvese chikamu chechiitiko ichi.
2.Modulation of (programmable) immune signing
Sezvataurwa pamusoro apa, ese mapoinzi apfuura anotungamira kune yakarongwa activation ye immune system.
Masero ekudzivirira anogona uye anoshandura mamiriro avo mukupindura kuCrystagen.
3.Kudzivirirwa Sero uye Homeostatic Maintenance
Crystalgen inoderedza oxidative kusagadzikana kukuvara zvakanyanya kune immune masero.
Kukwidziridzwa kweakasiyana intracellular antioxidants (glutathione kuva muenzaniso mukuru) ndiyo yekutanga nzira yekuita mukuita uku.
Panguva imwe chete, inhibition ye mitochondrial apoptosis nzira – kuburikidza nekutaura kwakadzorwa kwe BCl-2 mhuri mapuroteni – inocherechedzwa; yakaderedzwa apoptosis yemasero aya inotungamira kune nguva refu yekupona uye inotevera kushanda kutsungirira.
Kuchengeta yakagadzikana microenvironment mukati memuviri ndechimwe chinhu chakakosha Crystalgen inoratidzwa.
Regulating (uye kudzorera) chikamu chakakodzera cheakasiyana immune cell subsets ndeyekuti aya akawanda epasi rose ekudzivirira ekudzivirira anotangwa sei zvakare: kuongorora, kushingaira kudzivirira, uye clearance mabasa.
Kenza adjuvant therapy ndiyo imwe yeanonyanya kudiwa ekupedzisira mashandisirwo eiyi mutsara wekudzivirira immune.
COA
HPLC
MS
