I-GHK Copper Peptide (I-GHK-Cu Peptide okanye iCopper Peptide) yenziwe ngokuzenzekelayo metal complex phakathi kwe-GHK tripeptide kunye nobhedu(II) iiyoni. Uhlalutyo lweX-reyi lubonisa ukuba iglycine kwaye histidine iintsalela zisebenza njenge-ligands ezibophelela kwi-cation yentsimbi (Cu²⁺). Ikhonkco lecala lentsalela ye-lysine inokubandakanyeka ekuqapheliseni ii-receptors kwiiseli zesikhumba ezijoliswe kuzo. Iiyoni zobhedu zithatha inxaxheba kwiinkqubo ezahlukeneyo zokulwa nokuguga ngokusebenzisa i-enzyme catalysis.Zombini iinxalenye zeGHK-Cu – I-GHK ngokwayo kunye neCu2⁺ – zibambe ngokuzimeleyo, ukanti iyahambelana, iindima ekuthinteleni iinkqubo zokuguga.
Ulandelelwano
Gly-His-Lys-Cu
Inombolo yeCAS
89030-95-5
Ifomula yeemolekyuli
C14H23CuN6O4
Ubunzima beMolekyuli
401.91
Uphando lweGHK-CU / I-GHK Copper Peptide
Umahluko osisiseko phakathi kwe-GHK kunye ne-GHK-Cu ivela kwi-GHK yobudlelwane obuphezulu obuphezulu beeion zobhedu.. Oku kuhlobana kuthetha ukuba ngaphakathi kweemeko zebhayoloji eziqulethe iiyoni zobhedu, Ukubophelela okukhethiweyo kwenzeka; ukwenza iGHK-Cu ezinzileyo ngakumbi. Ngokupheleleyo, abaninzi ukuba ayingabo bonke, ye-GHK ye-biological imisebenzi idibene nale fomu yobhedu.
1.Iphuculwe antioxidant kwaye anti-ukudumba iipropati
I-Interleukin 6 (I-IL-6) yicytokine ephambili ebandakanyekayo kuyo ukudumba kwesikhumba kunye nokuphiliswa kwenxeba okulandelayo. I-GHK-Cu inciphisa ukukhuselwa kwale cytokine (yenziwe ngu I-tumor necrosis factor / TNF-α). Ukukhonza njengenye indlela corticosteroids okanye umxholo oqhelekileyo amayeza achasene ne-steroidal anti-inflammatory, ukunciphisa iziphumo ebezingalindelekanga ezinokubakho zokusetyenziswa kwexesha elide yenye yeempawu zayo ezibaluleke ngakumbi.
2.Ixhasa ikhonkco ukulungiswa kwezicubu kunye nohlengahlengiso
Glycosaminoglycans/GAGs (i-hyaluronic acid ukuba ngumzekelo obalaseleyo) bopha amanzi amaninzi, ukubonelela ulusu nge-hydration kunye nokugcwala okunempilo i-dermal matrix inikeza.
Iphantsi kakhulu, Uxinzelelo olungenatyhefu lwe-GHK-Cu luvuselela ukuhlanganiswa kunye nokuthotywa kwezi GlycosAminoGlycans/GAGs kunye ne-collagen. Ukuphiliswa kwenxeba, zonke iintlobo zokulungiswa kwesikhumba, ukuthungwa okuphuculweyo kunye nokunwebeka okwandisiweyo zonke zinempembelelo entle.
3.Ukhathalelo lwesikhumba kunye nokuchasana nokuguga
I-GHK-Cu ngoku ifakwe kwiiserum, iikhrimu, iikhrimu zamehlo njl. Inceda ukuqinisa ulusu, kunciphisa imigca emihle kunye nemibimbi, ngelixa ukukhanya kunye nokuguda kolusu zonke zibuyiselwe kancinci kancinci. Ukusetyenziswa kwayo njengonyango kukhokelela ekuphuculeni okubalulekileyo kweklinikhi kumsebenzi we-physiological wesikhumba.
4.Indawo yokunyamekela iinwele
I-GHK-Cu iphuhliswa njengokukhula kweenwele kunye nokuqinisa imveliso. Ukulahleka kweenwele (ukusa kwinqanaba elithile) inokulungiswa ngokuvuselela i-follicle kunye nokwandisa isigaba se-anagen somjikelezo. Uphando lubonisa inqanaba lokusebenza ngokuthelekiswa ne-minoxidil kwezi nkqubo.
5.Ukunyusa Ukuhlaziywa kweNeural (Ukuvuselelwa kwemithambo-luvo) kwaye Gene Expression
I-GHK-Cu ubuncinci i-arhente yokubuyisela. Ichaphazela uluhlu olubanzi lwezifo ezinxulumene nobudala. Uphononongo lweklinikhi kunye nolwangaphambili luyenziwa ukuvavanya konke oku kungentla, kunye nonyango lomntu lwexesha elizayo lunokungenelwa koku kungokwemvelo ngokwenene, peptide encinci yemolekyuli.
6.Isishwankathelo
I-GHK-Cu yipeptide encinci eneziphumo ezibalulekileyo zomzimba kumzimba womntu. Isetyenziswa ngokubanzi njengokukhula kweenwele kunye ne-cosmetic agent, kodwa kuyabonakala ukuba kukho imiqondiso eyongezelelweyo yeklinikhi.
Ukukwazi ukubandakanya iipeptide zendalo ezidityaniswe nobhedu kunyango zinesithembiso esikhulu sokuphucula iziphumo zesigulana kwiindawo ezinjengolawulo losulelo., ukuphiliswa kwenxeba, ukukhula kweenwele, kunye nomsebenzi wokuqonda.
I-COA
HPLC
NKSK
