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545.344V320h64V256H510.208A286.336 286.336 0 0 1 448 404.992v140.352L378.176 654.72 405.12 640h58.432l43.456-68.032 4.992-17.28V320h128v234.688l4.992 17.28 43.456 68.032h58.432l26.944 14.72zM320 896H192v128H128v-128H0v-64h128v-128h64v128h128z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i31.7a773a81Yn5fO8\" class=\"\"><\/path><path d=\"M256 128l-32 32L192 128V0h64zM88.256 43.008l-45.248 45.248 90.496 90.496h44.8v-45.504zM0 192v64h128l32-32L128 192z m43.008 167.744l45.248 45.248 90.496-90.496v-44.8h-45.504zM192 448h64V320l-32-32L192 320z m167.744-43.008l45.248-45.248-90.496-90.496h-44.8v45.504zM448 256V192H320l-32 32 32 32z m-43.008-167.744L359.744 43.008 269.248 133.504v44.8h45.504z\" fill=\"#515151\" data-spm-anchor-id=\"a313x.search_index.0.i33.7a773a81Yn5fO8\" class=\"selected\"><\/path><\/svg>\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" class=\"icon\" viewBox=\"0 0 1024 1024\" width=\"128\" height=\"128\"><path d=\"M752.64 864H399.36a65.92 65.92 0 0 1-15.36-2.112V768h-39.744c0.448-0.768 0.64-1.664 1.152-2.432L405.12 672h341.76l59.712 93.568a64 64 0 0 1-53.952 98.432z\" fill=\"#006758\" opacity=\".1\"><\/path><path d=\"M836.864 846.144a94.72 94.72 0 0 1-84.16 49.856H399.296A93.568 93.568 0 0 1 384 893.952v-66.112a29.952 29.952 0 0 0 15.296 4.16h353.408a32 32 0 0 0 26.944-49.28L729.6 704H422.4l-40.832 64h-72.32a96 96 0 0 1 9.152-19.648l59.712-93.632 27.008-14.72h341.76l27.008 14.72 59.712 93.568a94.976 94.976 0 0 1 3.264 97.856z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i30.7a773a81Yn5fO8\" class=\"\"><\/path><path d=\"M672 554.688V288H504.832A285.312 285.312 0 0 1 480 356.032v198.4L425.536 640h300.8z\" fill=\"#515151\" opacity=\".1\" data-spm-anchor-id=\"a313x.search_index.0.i32.7a773a81Yn5fO8\" class=\"selected\"><\/path><path d=\"M704 545.344V320h64V256H510.208A286.336 286.336 0 0 1 448 404.992v140.352L378.176 654.72 405.12 640h58.432l43.456-68.032 4.992-17.28V320h128v234.688l4.992 17.28 43.456 68.032h58.432l26.944 14.72zM320 896H192v128H128v-128H0v-64h128v-128h64v128h128z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i31.7a773a81Yn5fO8\" class=\"\"><\/path><path d=\"M256 128l-32 32L192 128V0h64zM88.256 43.008l-45.248 45.248 90.496 90.496h44.8v-45.504zM0 192v64h128l32-32L128 192z m43.008 167.744l45.248 45.248 90.496-90.496v-44.8h-45.504zM192 448h64V320l-32-32L192 320z m167.744-43.008l45.248-45.248-90.496-90.496h-44.8v45.504zM448 256V192H320l-32 32 32 32z m-43.008-167.744L359.744 43.008 269.248 133.504v44.8h45.504z\" fill=\"#515151\" data-spm-anchor-id=\"a313x.search_index.0.i33.7a773a81Yn5fO8\" class=\"selected\"><\/path><\/svg>\t\t<\/span>\n\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tliterature\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-16178233971\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-16178233971\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-75f6e59b e-con-full e-flex e-con e-child\" data-id=\"75f6e59b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-65ee387f e-flex e-con-boxed e-con e-child\" data-id=\"65ee387f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d17c86b elementor-drop-cap-yes elementor-drop-cap-view-default elementor-widget elementor-widget-text-editor\" data-id=\"d17c86b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;drop_cap&quot;:&quot;yes&quot;,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>At just two amino acids in length, Vilon is the shortest peptide known to have biological activity. Research shows that Vilon has potent anti-aging effects and that it is a powerful regulator of immune function. There is also good evidence that Vilon helps to regulate the vascular system and promotes hemostasis. Vilon has been shown to reduce the incidence and growth of spontaneous tumors, though its role as an adjuvant in cancer treatment (as opposed to prevention) has been called into question. Overall, Vilon has several staunch advocates, such as Dr. Vladimir Anisimov, who feel that the peptide is a useful geroprotective agent.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-16178233972\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-16178233972\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-39fdf57b e-con-full e-flex e-con e-child\" data-id=\"39fdf57b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-67358b1a e-flex e-con-boxed e-con e-child\" data-id=\"67358b1a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4a9d07d0 elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" 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data-spm-anchor-id=\"a313x.search_index.0.i76.7b0e3a8118k0Gw\" class=\"\"><\/path><path d=\"M701.44 339.616a33.872 33.872 0 0 0-3.424 47.784L805.928 512h86.392a33.816 33.816 0 0 0-6.44-11.176L749.232 343.048a33.872 33.872 0 0 0-47.784-3.432z\" fill=\"#666666\"><\/path><path d=\"M997.848 512h-183.216a107.448 107.448 0 0 1 91.608-51.2c38.728 0 72.68 20.48 91.608 51.2z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i77.7b0e3a8118k0Gw\" class=\"\"><\/path><path d=\"M838.096 600h-76.192v161.904H600v76.192h161.904V1000h76.192v-161.904H1000v-76.192h-161.904V600z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i75.7b0e3a8118k0Gw\" class=\"\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h5 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tSequence\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h5>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tLysylglutamate, normophthal, Lyslglutamic acid\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-396e2c4a elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"396e2c4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4fc81ebe elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" data-id=\"4fc81ebe\" 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78.768504 0 0 1-106.33748 29.932032 78.768504 78.768504 0 0 1-36.233512-48.836473 83.494614 83.494614 0 0 1 7.876851-61.439433 78.768504 78.768504 0 0 1 47.261102-37.808881 84.282299 84.282299 0 0 1 19.692126 0 78.768504 78.768504 0 0 1 39.384252 10.239905 83.494614 83.494614 0 0 1 36.233511 49.624157 85.069984 85.069984 0 0 1-7.87685 58.288693z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i191.7b0e3a8118k0Gw\" class=\"\"><\/path><path d=\"M270.963653 618.332754a10.239905 10.239905 0 0 0 10.239905-9.452221 278.840503 278.840503 0 0 1 236.305511-247.333101 10.239905 10.239905 0 0 0 8.664536-11.815276 9.45222 9.45222 0 0 0-11.027591-8.664535 295.381889 295.381889 0 0 0-252.846897 266.237542 9.45222 9.45222 0 0 0 8.664536 11.027591z m303.258739-267.025228a9.45222 9.45222 0 0 0 8.664535 11.027591 275.689763 275.689763 0 0 1 236.305511 247.333101 10.239905 10.239905 0 0 0 9.452221 8.664536 9.45222 9.45222 0 0 0 8.664535-11.027591 294.594204 294.594204 0 0 0-252.846897-265.449857 9.45222 9.45222 0 0 0-10.239905 9.45222z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i195.7b0e3a8118k0Gw\" class=\"\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h5 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tMolecular Formula\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h5>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tC176H277N57O55S7\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2f8e5988 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"2f8e5988\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f1efd3b elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" data-id=\"f1efd3b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" class=\"icon\" viewBox=\"0 0 1242 1024\" width=\"155.25\" height=\"128\"><path d=\"M881.892257 790.935454l-89.133129-30.532837c0.094822-2.180917 0.189645-4.267011 0.189645-6.447929 0-77.754431-59.264048-141.759603-135.027207-149.155756V419.705457h-74.245999v196.472172c-52.247185 22.56775-89.133128 74.056355-90.460643 134.268628l-205.859598 66.849846 20.955767 64.479284 198.842735-64.574106c23.895264 51.204138 75.763159 86.667744 135.880609 86.667744 58.126178 0 108.476914-32.998222 133.320403-81.357686l84.771294 29.110501 20.766123-60.686386z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i168.7b0e3a8118k0Gw\" class=\"selected\"><\/path><path d=\"M492.835634 755.661493v-3.982544c0-62.582835 39.351328-118.338451 98.330908-139.294219V421.507084c-10.904585-1.422337-21.903992-2.180917-32.903399-2.180917-160.060341 0.284467-289.3982 130.286083-289.01891 290.251602 0.094822 37.834168 7.585798 75.194224 21.998815 110.088896L492.835634 755.661493zM791.336791 751.678949c0.189645 2.844674 0.189645 5.594526 0 8.4392l48.928398 18.680028c6.068639-23.136684 9.19778-46.842304 9.387426-70.737567-0.284467-121.562416-76.521739-230.039329-190.877647-271.38193v167.740962c75.383869 7.965088 132.561823 71.496148 132.561823 147.259307zM774.45839 820.61489v-2.65503c-35.273961 73.297775-123.174398 104.209902-196.566994 69.030764-31.196595-14.981951-56.134906-40.489198-70.453101-72.065083v2.65503l-183.291848 57.367598c92.167448 130.096438 272.424976 160.818921 402.616237 68.651473 38.687571-27.403696 70.073811-64.005172 91.314046-106.485641l-43.61834-16.499111zM763.74345 141.685954c1.327515-76.901029-59.927805-140.337266-136.828834-141.66478-76.901029-1.327515-140.337266 59.927805-141.66478 136.828834-1.13787 66.091266 44.376919 123.932977 108.951026 138.251172v144.604277c12.801034-2.465384 26.076181-1.422337 38.30828 3.129142 9.861538 1.327515 19.15414 5.499704 26.739939 12.042454V275.10118c60.970853-15.645709 103.925435-70.4531 104.494369-133.415226zM1062.813543 753.859866c-44.945854 0.189645-86.193632 25.222779-107.244222 64.953397l-106.770109-40.015086c5.215236 23.041862-3.034319 47.031949-21.335057 61.824255l114.355907 47.600884c6.637573 66.755024 66.091266 115.493777 132.846291 108.856203s115.493777-66.091266 108.856203-132.84629c-6.163461-62.203545-58.600291-109.614783-121.183125-109.425138l0.474112-0.948225zM310.776478 879.404826c-6.637573-19.15414-16.024999-37.834168-25.317602-59.169226l-55.660794 16.878401C193.670719 780.599805 118.571317 764.005871 62.057121 800.228057c-56.514196 36.127364-73.013307 111.226766-36.885944 167.740962 36.127364 56.514196 111.226766 73.013307 167.740962 36.885944 34.894672-22.283282 56.040084-60.87603 56.040084-102.408276v-6.258283l61.824255-16.783578z\" fill=\"#515151\" data-spm-anchor-id=\"a313x.search_index.0.i169.7b0e3a8118k0Gw\" class=\"selected\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h5 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tMolecular Weight\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h5>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\t257.30\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-16178233973\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-16178233973\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-48f8d14 e-con-full e-flex e-con e-child\" data-id=\"48f8d14\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-74ecd939 e-flex e-con-boxed e-con e-child\" data-id=\"74ecd939\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6aa7aff6 elementor-widget elementor-widget-text-editor\" data-id=\"6aa7aff6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Vilon\u00a0 Related research<\/h3><p>Research out of Russia indicates that Vilon is a potent regulator of chromatin structure. One study found that Vilon:<\/p><p>\u2022 induces unrolling of chromatin,<\/p><p>\u2022 activates synthetic processes via reactivation of ribosomal genes in the unrolled chromatin,<\/p><p>\u2022 releases repressed genes, and<\/p><p>\u2022 does not cause decondensation of pericentromeric structural chromatin[1].nduces unrolling of chromatin,<\/p><p>The net result of the changes that Vilon causes to DNA is reactivation of genes that are otherwise silenced. In general, chromatin is found in either the wound (heterochromatin) or unwound (euchromatin) states. Heterochromatin cannot be accessed by the apparatus that turns genes into proteins and thus functional components of the cell. Genes in these regions of DNA are simply unavailable for protein production.<\/p><p>In general, chromatin helps to regulate which genes are available for transcription and is thus one way that different-cells can have different functions or that the same cells can have different functions over time. Unfortunately, chromatin condensation is also something that occurs as a result of aging and senescence and is at least one reason why our cells and tissues lose function as we get older.<\/p><p>Similar to its activity in lymphocytes, Vilon has been shown to activate interluekin-2 signaling in cells of the spleen[3]. Interleukin-2 is important in coordinating the immune response to microbial infection and helps to prevent autoimmune reactions. By activating lymphocytes and splenocytes while boosting natural protection against autoimmune reactions, Vilon restores the immune system to a more active state and may even be useful in developing treatments for autoimmune diseases.<\/p><p>Adding to its ability to prevent autoimmune reactions is the role of Vilon in the thymus. Research in thymus cultures shows that Vilon increases the proliferation of CD5 T-cells. CD5 is a marker of mature T-helper cells as well as cytotoxic CD8 T-cells. The former helps to regulate the immune system and prevent autoimmune reactions, while the latter is one of the most potent anti-microbial cells in the body[4].<\/p><p>Interestingly, Vilon appears to only reactivate immune functions via genes that have been silenced by changes in chromatin. It does not appear to activate genes that would naturally be silent in the cells it affects. In other words, Vilon does not turn lymphocytes into neurons by activating genes that would normally not be active in healthy lymphocytes. Instead, the peptide appears to boost activity in the immune system while simultaneously helping to prevent autoimmune reactions.<\/p><h6 class=\"Standard\">Vilon and Cancer<\/h6><p>As pointed out above, Vilon helps to reduce the incidence of cancer in mouse models, which is at least one way in which it prolongs average lifespan. Additional research shows that Vilon not only prevents tumors from forming, but inhibits their growth after they are present[5]. This suggests that Vilon may be both an effective chemotherapeutic in its own right, as well as a potential additive to existing cancer treatments. In the future, Vilon may be a standard addition to everything from chemotherapy to radiation treatment and surgery.<\/p><p>At least one study, out of Russia, contradicts the claim that Vilon may be a useful adjuvant to chemotherapy. The works shows that the combination of Vilon and platinum-based chemotherapeutic agents is problematic rather than synergistic[6]. Unfortunately, this study used only one specific type of chemotherapy and was limited in scope, so the results cannot be generalized. It remains to be seen if Vilon is only effective against cancer on its own or if the peptide can be added to other treatment regimens to boost results.<\/p><h6 class=\"Standard\">Vilon and Aging<\/h6><p>Research in mice shows that subcutaneous administration of Vilon increases physical activity and endurance while helping to reduce the risk of cancer. These two effects resulted in longer lifespan in the treated mice, suggesting that Vilon may be a legitimate anti-aging peptide[7]. This is especially encouraging given that it produced no adverse effects in the mice following long-term administration.<\/p><p>Interestingly, the research shows that the earlier Vilon is administered, the greater its effects seem to be. In other words, giving Vilon to young mice enhances lifespan more than if Vilon is not administered until the mice are much older. This same effect was seen in early studies looking at crude thymic and pineal extracts given to mice to slow down aging[8]. The speculation is that Vilon and similar peptides, when administered late in life, can reverse senescence in existing cells but can obviously do nothing for cells that have already been eliminated through apoptosis. By administering Vilon 20mg early in life, cells get the greatest amount of protection and so turnover is slowed down. The result is that more cells stay healthy for longer periods of time, slowing the need to replace them and preserving limited stem cell lines.<\/p><p>Vilon\u2019s anti-aging effects seem to extend to GI function as well, where the peptide has been shown to improve the activity of certain enzymes in the Gi tracts of older mice. The peptide also appears to improve barrier function, thus reducing the incidence of leaky gut, enhancing disease resistance, and improving the overall health of the GI tract in older mice[9]. Research shows that Vilon thereby helps to improve glucose and glycine absorption in the small intestine of older rats[10]. These features of Vilon may help to maintain nutrient extraction with age, thereby improving overall well-being and perhaps enhancing longevity.<\/p><p>Dr. Vladimir N. Anisimov, who has been researching aging and cancer development since the 1970s, points out that the thymus is one of two glands (the other being the pineal gland) that plays an important role in regulating aging. The healthier the thymus is, the healthier we are as individuals. Of course, Vilon is a thymic peptide and affects cells, like lymphocytes, that are produced in and mature in the thymus. Dr. Anisimov is a staunch advocate for using peptide bioregulators in the prevention of cancer[11]. He is a close colleague of Dr. Vladimir Khavinson.<\/p><h6 class=\"Standard\">Vilon in the Heart and Kidneys<\/h6><p>The effect of Vilon on the vasculature has been less well studied, but there is some work to suggest that it may have a beneficial effect. Research in mice shows that Vilon changes the expression of more than 36 different genes within the heart. When combined with Epithalon, this number jumps to 144 genes[12]. These findings suggest that, at the very least, Vilon has the ability to alter gene expression patterns in the cardiovascular system, a fact that may improve hemodynamic function.<\/p><p>In fact, research in kidneys, highly vascular organs, shows that Vilon decreases concentrations of transforming growth factor-beta(1) and thus the permeability of microvessels. The net result is improved hemostasis during kidney failure, suggesting that Vilon does, in fact, have a beneficial effect on the vascular system[13].<\/p><p>Furthermore, research in elderly patients with diabetes shows that Vilon can help to optimize coagulation by increasing levels of the natural anticoagulants antithrombin III and protein C while also stimulating fibrinolysis[14]. The result is fewer blood clots in a population prone to clotting and the serious consequences that follow. This further supports the idea that Vilon plays an important role in regulating the vascular system.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-16178233974\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-16178233974\" data-tab-index=\"4\" style=\"--n-tabs-title-order: 4;\" class=\" elementor-element elementor-element-94e44a3 e-flex e-con-boxed e-con e-child\" data-id=\"94e44a3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-664d1b9d e-con-full e-flex e-con e-child\" data-id=\"664d1b9d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-77280cd9 elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" data-id=\"77280cd9\" 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-6.31088 2.5729 Z m 46.7005 64.1768 a 9.19931 9.19931 0 0 1 -4.87879 1.48063 a 9.10222 9.10222 0 0 1 -7.45168 -4.10207 l -26.6028 -40.6323 a 9.1265 9.1265 0 0 1 2.59717 -12.5489 a 9.24786 9.24786 0 0 1 4.97588 -1.48063 c 2.93698 0 5.75261 1.48063 7.35459 4.05353 l 26.6028 40.6323 a 9.15077 9.15077 0 0 1 -2.59717 12.5974 Z\" fill=\"#86d2e9\" data-spm-anchor-id=\"a313x.search_index.0.i2.5b1c3a81rnqbFB\" class=\"\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tMS\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-16178233975\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-16178233975\" data-tab-index=\"5\" style=\"--n-tabs-title-order: 5;\" class=\" elementor-element elementor-element-3fe6dcd6 e-flex e-con-boxed e-con e-child\" data-id=\"3fe6dcd6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-55d35c17 e-con-full e-flex e-con e-child\" data-id=\"55d35c17\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11b8876c elementor-widget elementor-widget-text-editor\" data-id=\"11b8876c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a title=\" Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people \" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15105581\/\" target=\"_blank\" rel=\"nofollow noopener\">[1] T. Lezhava\u00a0<em>et al.<\/em>, \u201cBioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people,\u201d\u00a0<em>Biogerontology<\/em>, vol. 5, no. 2, pp. 73\u201379, 2004, doi: 10.1023\/B:BGEN.0000025070.90330.7f.<\/a><\/p><p><a title=\" Anti-aging peptide bioregulators induce reactivation of chromatin\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16705247\/\" target=\"_blank\" rel=\"nofollow noopener\">[2] T. Lezhava, J. Monaselidze, T. Kadotani, N. Dvalishvili, and T. Buadze, \u201cAnti-aging peptide bioregulators induce reactivation of chromatin,\u201d\u00a0<em>Georgian Med. News<\/em>, no. 133, pp. 111\u2013115, Apr. 2006.<\/a><\/p><p><a title=\" In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12447482\/\" target=\"_blank\" rel=\"nofollow noopener\">[3] T. B. Kazakova\u00a0<em>et al.<\/em>, \u201cIn vitro effect of short peptides on expression of interleukin-2 gene in splenocytes,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 133, no. 6, pp. 614\u2013616, Jun. 2002, doi: 10.1023\/a:1020210615148.<\/a><\/p><p><a title=\" Immunomodulating effects of Vilon and its analogue in the culture of human and animal thymus cells\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23486604\/\" target=\"_blank\" rel=\"nofollow noopener\">[4] N. N. Sevostianova\u00a0<em>et al.<\/em>, \u201cImmunomodulating effects of Vilon and its analogue in the culture of human and animal thymus cells,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 154, no. 4, pp. 562\u2013565, Feb. 2013, doi: 10.1007\/s10517-013-2000-0.<\/a><\/p><p><a title=\" A synthetic dipeptide vilon (L-Lys-L-Glu) inhibits growth of spontaneous tumors and increases life span of mice\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10944717\/\" target=\"_blank\" rel=\"nofollow noopener\">[5] V. K. Khavinson and V. N. Anisimov, \u201cA synthetic dipeptide vilon (L-Lys-L-Glu) inhibits growth of spontaneous tumors and increases life span of mice,\u201d\u00a0<em>Dokl. Biol. Sci. Proc. Acad. Sci. USSR Biol. Sci. Sect.<\/em>, vol. 372, pp. 261\u2013263, Jun. 2000.<\/a><\/p><p><a title=\" [Combined effect of vilon and cyclophosphane on tumor transplants and lymphoid tissue explants in mice and rats of various age]\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14743610\/\" target=\"_blank\" rel=\"nofollow noopener\">[6] O. P. Barykina, V. V. Iuzhakov, N. I. Chalisova, I. M. Kvetno\u012d, and S. S. Konovalov, \u201c[Combined effect of vilon and cyclophosphane on tumor transplants and lymphoid tissue explants in mice and rats of various age],\u201d\u00a0<em>Adv. Gerontol. Uspekhi Gerontol.<\/em>, vol. 12, pp. 128\u2013131, 2003.<\/a><\/p><p><a title=\" Effect of vilon on biological age and lifespan in mice\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11140587\/\" target=\"_blank\" rel=\"nofollow noopener\">[7] V. K. Khavinson\u00a0<em>et al.<\/em>, \u201cEffect of vilon on biological age and lifespan in mice,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 130, no. 7, pp. 687\u2013690, Jul. 2000, doi: 10.1007\/BF02682106.<\/a><\/p><p><a title=\" Effect of low-molecular-weight factors of thymus and pineal gland on life span and spontaneous tumour development in female mice of different age\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2682058\/\" target=\"_blank\" rel=\"nofollow noopener\">[8] V. N. Anisimov, A. S. Loktionov, V. K. Khavinson, and V. G. Morozov, \u201cEffect of low-molecular-weight factors of thymus and pineal gland on life span and spontaneous tumour development in female mice of different age,\u201d\u00a0<em>Mech. Ageing Dev.<\/em>, vol. 49, no. 3, pp. 245\u2013257, Sep. 1989, doi: 10.1016\/0047-6374(89)90075-4.<\/a><\/p><p><a title=\" Effect of vilon and epithalon on activity of enzymes in epithelial and subepithelial layers in small intestine of old rats\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12660839\/\" target=\"_blank\" rel=\"nofollow noopener\">[9] V. K. Khavinson, N. M. Timofeeva, V. V. Malinin, L. A. Gordova, and A. A. Nikitina, \u201cEffect of vilon and epithalon on activity of enzymes in epithelial and subepithelial layers in small intestine of old rats,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 134, no. 6, Art. no. 6, Dec. 2002.<\/a><\/p><p><a title=\" Effect of Vilon and Epithalon on glucose and glycine absorption in various regions of small intestine in aged rats\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12420071\/\" target=\"_blank\" rel=\"nofollow noopener\">[10 ]V. K. Khavinson, V. V. Egorova, N. M. Timofeeva, V. V. Malinin, L. A. Gordova, and L. V. Gromova, \u201cEffect of Vilon and Epithalon on glucose and glycine absorption in various regions of small intestine in aged rats,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 133, no. 5, pp. 494\u2013496, May 2002, doi: 10.1023\/a:1019878224754.<\/a><\/p><p><a title=\" [The use of peptide bioregulators for cancer prevention: results of 35 years of research experience and perspectives]\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19670728\/\" target=\"_blank\" rel=\"nofollow noopener\">[11] V. N. Anisimov and V. K. Khavinson, \u201c[The use of peptide bioregulators for cancer prevention: results of 35 years of research experience and perspectives],\u201d\u00a0<em>Vopr. Onkol.<\/em>, vol. 55, no. 3, pp. 291\u2013304, 2009.<\/a><\/p><p><a title=\" Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12360356\/\" target=\"_blank\" rel=\"nofollow noopener\">[12] S. V. Anisimov, K. R. Bokheler, V. K. Khavinson, and V. N. Anisimov, \u201cStudies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 133, no. 3, pp. 293\u2013299, Mar. 2002, doi: 10.1023\/a:1015859322630.<\/a><\/p><p><a title=\" Effect of peptide Vilon on the content of transforming growth factor-beta and permeability of microvessels during experimental chronic renal failure\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16142267\/\" target=\"_blank\" rel=\"nofollow noopener\">[13] N. A. Gavrisheva, V. V. Malinin, T. P. Ses, K. L. Kozlov, A. V. Panchenko, and A. Y. Titkov, \u201cEffect of peptide Vilon on the content of transforming growth factor-beta and permeability of microvessels during experimental chronic renal failure,\u201d\u00a0<em>Bull. Exp. Biol. Med.<\/em>, vol. 139, no. 1, pp. 24\u201326, Jan. 2005, doi: 10.1007\/s10517-005-0202-9.<\/a><\/p><p><a title=\" [Effect of vilon on the immunity status and coagulation hemostasis in patients of different age with diabetes mellitus]\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18306698\/\" target=\"_blank\" rel=\"nofollow noopener\">[14] B. I. Kuznik, N. V. Isakova, N. N. Kliuchereva, N. V. Maleeva, and I. S. Pinelis, \u201c[Effect of vilon on the immunity status and coagulation hemostasis in patients of different age with diabetes mellitus],\u201d\u00a0<em>Adv. Gerontol. Uspekhi Gerontol.<\/em>, vol. 20, no. 2, pp. 106\u2013115, 2007.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-39a951c2 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"39a951c2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d8a631a elementor-widget elementor-widget-icon-box\" data-id=\"4d8a631a\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tArticle\/Literature Citation Notes\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tThe purpose of quoting the scientist and professor's article is to acknowledge, recognise and applaud the exhaustive development work that has been done to undertake this peptide research. The scientist does not in any way support or advocate the purchase, sale or use of this product for any reason, and MOL Changes has no affiliation or relationship, implied or otherwise, with the scientist.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-a894aef e-flex e-con-boxed e-con e-parent\" data-id=\"a894aef\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-62417cad elementor-position-inline-start elementor-view-default elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"62417cad\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" class=\"icon\" viewBox=\"0 0 1098 1024\" width=\"137.25\" height=\"128\"><path d=\"M610.892409 345.817428C611.128433 343.63044 611.249529 341.409006 611.249529 339.159289 611.249529 305.277109 583.782594 277.810176 549.900416 277.810176 516.018238 277.810176 488.551303 305.277109 488.551303 339.159289 488.551303 339.229063 488.55142 339.298811 488.551654 339.368531L488.36115 339.368531 502.186723 631.80002C502.185201 631.957072 502.184441 632.114304 502.184441 632.271715 502.184441 658.624519 523.547611 679.98769 549.900416 679.98769 576.253221 679.98769 597.616391 658.624519 597.616391 632.271715 597.616391 631.837323 597.610587 631.404284 597.599053 630.972676L610.892409 345.817428ZM399.853166 140.941497C481.4487 1.632048 613.916208 1.930844 695.336733 140.941497L1060.013239 763.559921C1141.608773 902.869372 1076.938039 1015.801995 915.142835 1015.801995L180.047065 1015.801995C18.441814 1015.801995-46.243866 902.570576 35.176659 763.559921L399.853166 140.941497ZM549.900416 877.668165C583.782594 877.668165 611.249529 850.201231 611.249529 816.319053 611.249529 782.436871 583.782594 754.96994 549.900416 754.96994 516.018238 754.96994 488.551303 782.436871 488.551303 816.319053 488.551303 850.201231 516.018238 877.668165 549.900416 877.668165Z\" fill=\"#FB6547\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\twarning\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tThese products are intended for scientific purposes only for in vitro research and are not to be used for human, animal or unethical experiments, in vitro research (Latin: in glass) is conducted in vitro.\nThese products are not drugs and are not approved by the Food and Drug Administration in any country for the prevention, treatment or cure of any medical condition, disease or illness. The introduction of this product into humans or animals in any form is strictly prohibited by law.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b5e39a3 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"5b5e39a3\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u5df2\u77e5 Vilon \u5bf9\u6dcb\u5df4\u7ec6\u80de\u7ed3\u6784\u548c\u5b64\u96cc\u751f\u6b96\u5f02\u67d3\u8272\u8d28\u6709\u5f71\u54cd\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>","protected":false},"featured_media":9925,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[99],"product_tag":[],"class_list":{"0":"post-2045","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-immunomodulation","8":"first","9":"instock","10":"purchasable","11":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/product\/2045","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/comments?post=2045"}],"version-history":[{"count":0,"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/product\/2045\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/media\/9925"}],"wp:attachment":[{"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/media?parent=2045"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/product_brand?post=2045"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/product_cat?post=2045"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/molchanges.com\/zh\/wp-json\/wp\/v2\/product_tag?post=2045"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}