Biotinoyl Tripeptide-1

Nnyocha nke Biotinoyl Tripeptide-1

Isi ihe nhazi nke Biotinoyl Tripeptide-1 n'onwe ya bụ tripeptide GHK a.. Emeela nyocha sara mbara na ọrụ GHK dị iche iche nke ndu ndu – mmezi anụ ahụ, mgbochi mbufụt bụ isi ihe atụ abụọ, na mgbochi ịka nká bụ akụkụ a mụrụ n'oge na-adịbeghị anya.

Biotin dị ka isi coenzyme na-akwado njikọ nke keratin (protein bụ isi dị na ntutu isi); Ịkwado ahụike ntutu bụ otu n'ime ọrụ ọ na-arụ mgbe niile. Ijikọta ya na peptide na-enye nkwado nri ọzọ nwere ike ime, mana ihe kacha mkpa bụ biotin dị nso na mmekọrịta zuru oke maka mkpụrụ ndụ follicle ntutu; na-emeziwanye arụmọrụ njide na saịtị ndị a ezubere iche, bioavailability na ruo n'ókè arụmọrụ [1].

Nnyocha na-egosi njigide na-aga nke ọma nke njide ọla kọpa GHK, dị iche iche antioxidant na mgbochi glycation ọrụ; nnyefe ezubere iche bụ isi nkwalite biotin na-enye ohere. Mgbochi dị mkpa nke acrolein (ACR)-emelitere Aβ carbonylation (ihe nrịbama mmebi oxidative) na mbelata nguzobe nke kwuru adducts hụrụ.

Ascorbic acid oxidation catalyzed site na Cu(II)-Akwụsịkwara mgbagwoju Aβ, na-ebelata ihe niile sochirinụ ụdị oxygen reactive (ROS) ọgbọ (ọzọ, A na-ahụ arụmọrụ nke ọma ma e jiri ya tụnyere GHK dị ọcha, ndị ji C-ọnụ ọnụ ịbụ ihe nwere ike ime).

Nyocha Spectrophotometric (2-(4′-Hydroxyazobenzene) Benzoic acid/HABA nchụpụ) akwadoro streptavidin dị elu site na Biotinoyl Tripeptide-1 – A na-edobe ebumnuche ọkwa biotin dị ọcha.

Biotinoyl Tripeptide-1 bụ ma na-anọgide na-abụ peptide biotinylated pụrụ iche, na ma ọ bụ na-enweghị ngwa ịchọ mma, n'echiche niile na ebumnuche akwụkwọ akụkọ nke nwere oke mmasị ma sayensị ma onye ọrụ njedebe.

Biotinoyl Tripeptide-1 na-ejikọta ya na ihe ndị ọzọ na-eme ihe na-egbochi ntutu isi; minoxidil, finasteride, ụdị dị iche iche nke ihe ọkụkụ (hụrụ palmetto ịbụ ezigbo ihe atụ, salvia miltiorrhiza na ginkgo biloba na-amụkwa nke ọma), vitamin (biotin ma ọ bụrụ na m chetara nke ọma na ọ bụ ihe a na-ahụkarị, nnukwu vitamin B), na ihe ndị dị ka zinc na selenium.

Ngwakọta ahụ na-agbaso usoro ọgwụgwọ ọtụtụ ebumnuche – na-ekwu ihe m kwenyere na ọ bụ otutu, usoro pathophysiological n'out oge nke ntutu isi.

Biotinoyl Tripeptide-1 n'onwe ya bụ peptide multifunctional, ihe si n'ụdị ụfọdụ nke injinịa molekul. Mgbanwe nke mmetụta GHK, antioxidant na ruo n'ókè a na-ejikọta ihe ndị na-akpata neuroprotective nke ọma na ikike nnyefe nke biotin.

Azụmahịa na ịchọ mma ubi o guzobewo onwe ya dị ka ma mgbochi ịka nká na (nso nso a) ihe na-akwalite ntutu isi. Mgbochi nke amyloid a kpọtụrụ aha na mbụ na-akwalite nyocha n'ihu; ọrịa neurodegenerative, Ọrịa Alzheimer nke ọma, na-ekwe nkwa n'ọdịnihu ngwa.

Nnyocha miri emi na nke sara mbara ga-akọwakwuo ọnọdụ Biotinoyl Tripeptide-1 n'ihe omume niile nke ahụike na ọrịa mmadụ..