Myristoyl Hexapeptide-23

Nnyocha nke Myristoyl Hexapeptide-23

A na-emepụta ụdị peptide a gbanwere site na njikọ nke covalent; a na-ejikọta usoro hexapeptide myristic acid (tetradecanoic acid). Mkpụrụ ndụ myristoyl n'onwe ya na-eje ozi dị ka eriri lipid hydrophobic, na-abawanye mkpokọta hydrophobicity nke peptide.

Ngwongwo a na-akwalite ntinye akpụkpọ ahụ na nnabata na-esote. Injinia peptide iji lekwasịrị anya ụfọdụ nchegbu anụ ahụ – ihe otutu bụ isi ihe atụ, yana ọnọdụ mkpali niile metụtara ya sitere na nje nje microbial – bụ akụkụ nke imewe ya.

Kemịkalụ nkewa dị ka peptide antimicrobial, ihe mgbakwunye mgbochi mkpali na 'nrụzi’ Ọrụ ọ na-egosipụta karịrị igbu nje bacteria dị mfe.

Myristoyl Hexapeptide-23 na-egosipụta ọrụ ụdịdị dị iche iche kwuru, P. acnes bụ otu n'ime nje bacteria na-egbochi nke ọma.

Propionibacterium acnes bi n'ime ime ntutu isi na pores, elu onwe ya, na-adabere na sebum, obere irighiri ihe cellular na nso nso nso a na-emepụta ihe ndị na-emepụta ihe na-emepụta ihe na-eme ka akpụkpọ ahụ dị gburugburu dị ka ma isi iyi ume na nri dị iche iche.

Sebaceous glands na-emebiga ihe ókè na-eduga na ụbara (ma ọ bụ opekata mpe nwa oge anaghị achịkwa ya) mmepụta nke sebum; mgbochi follicle na-esote. Mgbe ahụ nje bacteria na-amụba, na-emepụta ọtụtụ protein – na-agbaji sebum na ihe niile na-esote, nke anụ ahụ na nke metabolic na-emebi iguzosi ike n'ezi ihe nke mgbidi follicle.

Mgbasa ngwa ngwa na-eduga na nzaghachi mkpali niile a kpọtụrụ aha na mbụ; folliculitis, otutu otutu, wdg.

Ugbu a, a na-eji Myristoyl Hexapeptide-23 na ngwaahịa nlekọta anụ ahụ maka mmanu mmanu, ihe otutu na-afụ ụfụ.

Data dị n'ihu ọha iji kwado ma ọ bụ gbaghaa nrụpụta ya n'ịgwọ ihe otutu na ọnọdụ niile metụtara ya, Otú ọ dị, ka na-efu.