Acetil Tetrapeptido-9

Esplorado De Acetil Tetrapeptido-9

Acetil-tetrapeptido-9 estas ĉefe poziciigita kiel "dermal restrukturilo".’ La struktura integreco kaj ĉiuj rilataj mekanikaj trajtoj de la haŭto dependas peze de la eksterĉela matrico (ECM); kolagena fibro-kvalito kaj posta aranĝo estas de aparta graveco. Maljuniĝo kondukas al malpliigita ECM-sintezo kaj pliigita degenero, a disruption of what was once a well ordered collagen network – visible signs of aging (wrinkles, laxity being prime examples) follow. The development objective of this peptide is systematic improvement and in some cases restoration, of this healthy dermal structure; intervention at the level of key ECM component synthesis being the means to achieve it.

The uniqueness of Acetyl Tetrapeptide-9 lies not solely in directly promoting Type I collagen production, but more critically in its action on a near ‘organizer’ of said collagen assembly – lumican. Research has shown significant upregulation of the α1 chain of Type I collagen (COL1A1) kaj lumican gena esprimo. Experimental data confirm increased fibroblast secreted levels of both proteins; Type I collagen and to a large extent lumican itself.

Studo implikanta 17 inaj volontuloj (aged 45-55) used a cream containing 0.9% Dermican™ for 16 semajnoj. Ultrasound and clinical skin palpation evaluations were the measures of improvement; thickness and firmness both showed positive changes. By the 8-week mark at least 82% reported noticeable improvement in all aspects of skin firmness.

Acetyl Tetrapeptide-9 exhibits excellent stability and can be combined with other actives (vitamin C, hyaluronic acid, sunscreens etc.) to enhance photoprotection. Synergistic effects with other peptides are well documented.

Anti-aging is a functional process and Dermican™ is a part of a true and measurable dermal remodeling. Skin firmness and thickness, to all intents and purposes, is a success of this line of active peptides.