Oxytocin

Noi'i pili o Oxytocin

1.Hoʻoulu ʻana Hoʻopaʻa ʻana o ka ʻōpū

Mai kona ʻike ʻana, Ua hoʻohana mua ʻia ka oxytocin no kēia kumu kikoʻī – hoʻoulu i ka ʻōpū o ka ʻōpū, hana i nā kūlana kūpono no ka hānau ʻana. Hoʻopili ia i nā mea loaʻa oxytocin (he ano o ʻO ka mea hoʻokipa i hui pū ʻia me ka protein G) aia ma luna o nā ʻiʻo ʻiʻo maʻemaʻe o ka ʻōpū. Hoʻoulu ʻia o kikoʻī nā ala calcium i loko ka membrane cell alakai i ka pii nui o calcium intracellular hoʻopaʻa ʻana.

Myosin kaulahao kinase a laila ho'ā, ʻo ka hopena i nā ʻokiʻoki ʻana i ʻōlelo ʻia ma mua o ka liʻiliʻi o ka ʻiʻo maʻemaʻe endometrial. ʻO kēia mau 'luna-lalo’ ʻO nā ʻokiʻoki like loa me ka hoʻokuke lima ʻana i ke keiki i waho.

Ua hōʻike ʻia nā hoʻokolohua lapaʻau i ka hoʻokele intravenous e hōʻemi i nā wā ʻoki i waena 2-3 minuke; ʻO ka hoʻolōʻihi ʻana o ka lōʻihi he hopena i kākau maikaʻi ʻia, hana ʻia nā ʻokiʻoki hana maikaʻi ma laila. Ke hōʻike nei nā noiʻi hou aʻe ʻaʻole ʻo ka oxytocin-induced contractions he mea hana maʻalahi i ka lawe ʻana., ka pani ʻana o ka vascular ma hope o ka hānau ʻana ma ke kahua kaʻawale (ʻO ka pale ʻana i ka hemorrhage kekahi o nā hopena koʻikoʻi) e pāʻani ana i kahi kūlana koʻikoʻi.

2.Hoʻolaha ʻia ka waiu waiu

ʻO ka hoʻokuʻu ʻana o ka waiū e pili ana i ka ʻōnaehana neuroendocrine reflex, ka let-down reflex. Hāʻawi ke keiki hānai i ka nipple o ka makuahine i ka hoʻoulu mua, nā aʻalolo e hoʻouna ana i nā hōʻailona i ka hypothalamus. Hoʻopili ʻia ka oxytocin a hoʻokuʻu ʻia ma laila, ka hele ʻana ma ke kahe koko e hana ma luna o nā cell myoepithelial (a puni ka mammary alveoli a me nā ducts liʻiliʻi), ʻO ko lākou ʻoki ʻana ʻo ia ka hopena o ka hoʻokuʻu ʻana i ka waiū.

Ua ʻike ʻia kahi haʻawina i ka hana ʻana o ka makuahine i nā ʻiole wahine ma hope 3 hora hookeai, ʻO ka hoʻoheheʻe waiu ikaika kekahi o nā ʻano hana i hoʻopaʻa ʻia. Ua hoʻihoʻi hou ka oxytocin exogenous i kēia ʻano – hōʻoia pololei o kona pono i ka paipai ʻana i ka waiu ejection.

3.Hoʻolaha ʻana i ke ʻano Prosocial

Hoʻopili paʻa ʻia nā pilina pili kanaka i loko o ka lolo kanaka. Hoʻohana ka poʻe ponoʻī ma mua ka orbitofrontal cortex (OFC) e hana i nā ʻano āpau o ka 'waiwai waiwai', prosocial kanaka oi aku ka amygdala. ʻO ka hāʻawi like ʻana he hopena prosocial kūlohelohe.

Ua hōʻike ʻia ka hoʻokele o Oxytocin e hoʻohuli i ka poʻe paʻakikī i ka ʻano prosocially.

4.Hoʻoponopono maʻi maʻi a me ka hoʻoponopono ʻana i ka ʻili

ʻO ka maʻi puʻuwai ʻo ia ke kumu nui o ka make ma ka honua holoʻokoʻa. ʻO ka hōʻeha o ka myocardial hopena i ka nui make cardiomyocyte; ʻO ka nele loa o ka hiki ke hoʻoponopono pono iā ia iho i loko o nā cardiomyocytes makua he mea keakea mua i kekahi ʻano o ka hoʻihoʻi ʻana i ka naʻau..

Ma hope o ka hōʻeha cryogenic i nā puʻuwai zebrafish, Ua ʻike nā mea noiʻi i ka hoʻonui nui ʻana o ka oxytocin mRNA hōʻike i ka lolo, ka hopena o ka piʻi ʻana o ka oxytocin i loko o ka puʻuwai ponoʻī. ʻO ke kāohi kemika o kēia ʻōlelo oxytocin i hoʻopaʻa nui i nā kaʻina hana hoʻoponopono puʻuwai hiki ke ana – ʻO ka hoʻouluʻana o nā pūnaewele epicardial hou kekahi o nā hiʻohiʻona kaulana loa.

This study was the first to clearly define oxytocin’s crucial, promotive role in at least some aspects of cardiac cell repair.

5.Anti-inflammatory

In various forms of cardiovascular disease, constant low-grade inflammation and the associated oxidative stress are another near universal barrier to proper cell repair. Oxytocin significantly suppresses the release and subsequent expression of multiple pro-inflammatory factors, reduces the generation of true inflammatory cells, and through enhanced (endogenous) antioxidants like glutathione peroxidase, mitigates all aspects of that oxidative damage.

6.Regulating Appetite and Metabolism

Oxytocin plays a well documented key role in both appetite and more general metabolism. Synthesized in hypothalamic neurons that project to near all brain regions, it amplifies satiety signals (brainstem based) – a near immediate strong ‘fullness’ being the end result of feeding.

Direct central nervous system action on dopamine seeking pathways reduces the motivation to seek out high reward foods (fat/sugar being prime examples). Studies have also shown oxytocin to increase insulin from pancreatic β-cells, and enhance glucose homeostasis.