Tetrapeptide-26 (Lub npe lag luam Chronogen®) yog ib qho khoom siv hluavtaws los tiv thaiv kev laus tetrapeptide uas tau raug tsim los ntawm lub xeev-of-the-art molecular biology, nrog cov qauv tsim hauv paus hauv thaj tsam ntawm epigenetics.
Nws cov amino acid sequence yog H-Ser-Pro-Leu-Gln-NH2 thiab nws qhov hnyav molecular yog kwv yees li. 442.51 – 443.49 Nws.
Nws feem ntau yog cov hmoov dawb nrog lub purity feem ntau tshaj 95% rau 98%, thiab muaj cov dej-solubility zoo heev.
Raws li ib tug cosmetic active nws yog tshwj xeeb tsim los pab txhawb cov tawv nqaij circadian suab paj nruag, ua kom nws tiv thaiv kev cuam tshuam sab nraud thaum nruab hnub thiab txhawb kev rov tsim dua thaum hmo ntuj.
Ib ntus
Ser-Pro-Leu-Gln-NH2
CAS Nr
1234463-61-6
Molecular Formula
C19H34N6O6
Molecular Luj
442.51
Tetrapeptide-26 Kev Tshawb Fawb Txog Kev Tshawb Fawb
1.Core tswvyim thiab Mechanism of Action
Raws li ib qho ntawm Tetrapeptide-26 lub npe lag luam yog Chronogen®, ib lub npe qhia nws qhov tseem ceeb ntawm kev ua ub no nyob rau hauv kev sib raug rau "lub sij hawm" (Chrono) thiab kev tswj cov noob - nws ua los ntawm kev hloov kho ntawm daim tawv nqaij circadian atherosclerosis moos uas pab txhawb rau nws cov nyhuv tiv thaiv kev laus.
Ua ib lub siab purity hluavtaws peptide, nws yog feem ntau muab tso rau ntawm kab nyob rau hauv cov qauv thiab yuav tsum tau khaws cia hauv qab txias, qhuav tej yam kev mob thiab tiv thaiv los ntawm lub teeb kom muaj stability¹.
Kev tiv thaiv kev laus ntawm Tetrapeptide-26 ua tiav tsis yog los ntawm cov pa inhibition lossis ua kom muaj kev cuam tshuam ntawm kev taw qhia tab sis dhau los ntawm kev tswj hwm kev tswj hwm ntawm epigenetic., Feem ntau tsom rau lub sijhawm lom neeg sab hauv ntawm daim tawv nqaij.
2.Circadian Rhythm Genes Modulation
Tetrapeptide-26 pab rov kho tus kheej lub peev xwm thoob plaws nruab hnub hmo ntuj los ntawm kev tswj cov theem ntawm cov tub ntxhais circadian noob suav nrog CLOCK, BMAL1 thiab PIB 1, uas cuam tshuam los ntawm ultraviolet (UV) kev puas tsuaj.
3.DNA Kho Txhawb nqa
Qhov no peptide induces daim tawv nqaij lub peev xwm los kho DNA puas los ntawm UV raug (xws li sunburned cell) thiab ua kom cov synthesis ntawm collagen fibers nyob rau hauv daim tawv nqaij kom txhim kho elasticity thiab firmness ².
4.Anti-photoaging
Tetrapeptide-26 txo cov cim ntawm kev laus xws li wrinkles, cov kab zoo, thiab daim tawv nqaij laxity los ntawm inhibiting molecular txoj kev cuam tshuam rau kev yees duab.
Tetrapeptide-26 feem ntau yog siv nyob rau hauv high-end anti-aging tshuaj pleev ib ce, xws li hmo ntuj serums thiab ampoules, txhawm rau ua kom cov tawv nqaij kho qhov siab tshaj plaws thaum pw tsaug zog, li no txhim kho cov khoom nkag mus thiab ua haujlwm tau zoo.
Nws nquag tsim ua ke nrog lwm cov peptides (piv txwv, Acetyl Tetrapeptide-9) los yog cog extracts (e.g., Albizia Julibrissin Bark Extract), qhov twg lawv synergistically ua hauj lwm kom tsawg glycation-induced kev puas tsuaj thiab txo cov tsos mob ntawm qaug zog, muab cov txiaj ntsig zoo tiv thaiv kev laus ³.
Tetrapeptide-26 sawv cev rau txoj hauv kev tshiab hauv kev tiv thaiv kev laus raws li epigenetic thiab circadian rhythms.
Nws qhov txiaj ntsig zoo tshaj plaws yog ua tiav cov tawv nqaij rejuvenation los ntawm ntau lub hom phiaj mechanisms (kho DNA, kev cai sib dhos, collagen synthesis).
Txawm hais tias feem ntau cov kev tshawb fawb tau ua nyob rau hauv vitro los yog raws li kev soj ntsuam ua ntej, nws daim ntawv thov nyob rau hauv tshuaj pleev ib ce twb tau validated.
COA
HPLC
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