Пептид CRO

Provide peptide technology exploration for pharmaceutical and biotechnology companies or research institutions; process development services.

Барање за понуда

Peptide CRO Advantage

Класа 100 стерилна лабораторија

Специјалист за органска хемија

Достапно во одделение mg-kg

Чистота од сурова до 99%

Multi-modal study routes

Peptide CRO Core Services

Technology development; process mapping.

Design and Synthesis

Customized peptide synthesis

Synthesize peptides of specific sequences (на пр. linear peptides, циклични пептиди, modified peptides, итн.) according to customer requirements.

Modification types

фосфорилација, ацетилација, biotin labeling, fluorescent labeling (FITC, Cy series), ПЕГилација, итн.

Special structural peptides

disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (CPP), glycosylated peptides, итн.

Peptide library construction

Provide combinatorial peptide libraries (на пр. phage display libraries, solid phase synthesis libraries) for high throughput screening.

Process Development

Route design

Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (usually ≤50 амино киселини), need to select protection group strategy, реагенси за спојување, итн.

Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (на пр. Е. coli, yeast) and culture conditions..

Process optimization

Synthesis/expression optimization: increase yield (на пр. температура, pH вредност, catalyst concentration).

Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.

Impurity control: remove missing peptides, mismatched sequences, производи за оксидација, итн. to ensure purity (usually >98%).

Производи

Вести