Acetyl Tetrapeptide — 3 ge 'nar sintético biomimético péptido compuesto ya goho residuos ar aminoácidos.
jar últimos ya je̲ya xi ganado significativa Ntheti komongu ingrediente activo mbo cosméticos ne dermatología; productos da promueven crecimiento ya pelo ne da japi pérdida ar pelo komongu ar ejemplos ar primo.
Secuencia
Ac-Lys — Gly — H — Lys
'bede ya CAS
827306-88-7
Fórmula molecular
C22H38N8O6
Be̲xu molecular
510.61 g yá mol
Nthoni Ar Acetil Tetrapéptido — 3
Nt'ot'e mbo central ar nt'ot'e pa nuna ar péptido ar Hmunts'i wa indirectamente estimulando fibroblastos dérmici ne células papilla dérmicas (DPCs) pa sintetizar ne secretar clave colágeno ar klase III.
colágeno ar klase III hä xkagentho ge 'nar 'bu̲i 'bu̲i mahyoni estructuralmente jar capa dérmica ar piel, tejido conectivo específicamente rodea ar folículo capilar – flexible structural support being the primary function attributed to it.
Following treatment with Acetyl Tetrapeptide-3, quantitative analysis showed a +65% increase in Type III collagen expression, laminin being another closely tracked marker (+285% increase).
Type VII collagen forms the primary anchoring fibers, firmly linking the basement membrane to the dermis below.
Research has shown Acetyl Tetrapeptide-3 reversing cortisol-induced declines in this collagen type, thereby repairing and reinforcing the dermal-epidermal junction (DEJ) structure.
Acetyl Tetrapeptide-3 enhances hair follicle adhesion to the scalp, while also promoting new follicle development.
In vitro and ex vivo studies have comprehensively validated the previously mentioned mechanism.
Nanoliposomes composed of copper peptides, Acetyl Tetrapeptide-3 and myristoyl pentapeptide-4 have been proven to promote hair growth through all the above pathways.
Clinical efficacy has been established.
A 24-week, randomized, triple-blind controlled trial compared the herbal formulation (containing Acetyl Tetrapeptide-3 as part of its active ingredients) to 3% minoxidil, and demonstrated comparable efficacy in treating androgenetic alopecia with a favorable safety profile.
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