Oligopeptides 24 yog ib tug hluavtaws bioactive peptide precisely tsim los ntawm 13 amino acid residues.
Muab los ntawm ib qho enzyme cleaved fragment ntawm elastin, nws muaj qhov tshwj xeeb lom neeg ua haujlwm.
Kev kho kom zoo tsis tu ncua, kev tshuaj ntsuam, thiab kev ua kom zoo ib ntus tau siv los txhim kho nws transdermal absorption muaj peev xwm.
Lub hom phiaj suav nrog disulfide bonds pab kom stabilize nws cov qauv.
Cov kev hloov kho no tsis txo qis nws txoj haujlwm lom neeg; qhov tseeb, natural protein cov haujlwm bioactive yog khaws cia ntau.
Ib ntus
Cys-Met-Tyr-Ile-Glu-Gly-Gly-Gly-Gly-Arg-Gly-Asp-Gly
CAS Nr
1018685-16-9
Molecular Formula
C50H78N16O19S2
Molecular Luj
1271.39
Kev tshawb fawb txog Oligopeptide-24
1.Txhim kho Elastin Functionality
Mimicking lub physiological luag hauj lwm ntawm endogenous elastin, Nws txhawb nqa elastin synthesis hauv lub cev dermis; tawv elasticity, kev ruaj khov, thiab hydration tag nrho yog txhim kho.
Plumped ntaub so ntswg, smoothed zoo kab, thiab tag nrho cov kev hloov pauv zoo hauv kev ntxhib los mos yog cov txiaj ntsig ncaj qha ntawm cov txheej txheem no.
Direct stimulation ntawm fibroblasts (kev loj hlob thiab kev ua haujlwm) ua rau kom muaj zog collagen synthesis – noj qab nyob zoo , daim tawv nqaij hluas dua yog qhov kawg tshwm sim.
Thaum nkag mus rau ntawm daim tawv nqaij ntawm kev xa khoom, Oligopeptides 24 khi rau cov receptors tshwj xeeb ntawm cov chaw fibroblast.
Elastin signaling yog mimiced, intracellular txoj kev raug qhib; tus kev sau ntawv ntawm elastin noob nws tus kheej yog qhov tseem ceeb.
Cov tawv nqaij firmness thiab suppleness tau zoo heev, compensating rau cov ntaub ntawv zoo poob (kev yees duab) ua rau natural elastin ntau lawm.
Generation ntawm 'qhov chaw’ proteins yog dab tsi tiag restores cov laus daim tawv nqaij mus rau ib tug ntau hluas.
2.Activates Fibroblast Activity thiab Stimulates Collagen Synthesis
Raws li tau hais los saum no, Lub hom phiaj ncaj qha ntawm fibroblasts yog ib qho ntawm cov teebmeem tseem ceeb Oligopeptide 24 kev tawm dag zog.
Nws txhim kho tag nrho cov haujlwm metabolic ntawm fibroblasts, stimulating lawv faib thiab proliferation.
Nws txhawb kev tsiv teb tsaws sai mus rau thaj chaw puas, txhim kho lawv lub xeev kev ua haujlwm hauv synthesizing extracellular matrix thiab stimulating ntau lawm ntau hom I thiab III collagen, ntxiv consolidating daim tawv nqaij firmness moj khaum.
Cov tawv nqaij kho tus kheej thiab kev muaj peev xwm rov tsim dua tshiab, ua rau muaj kev noj qab nyob zoo.
3.Strengthes Skin Barrier thiab Hydration Function
Oligopeptides 24 activates lub integrin α6β4 → PI3K → Akt axis, stimulating keratinocytes rau secrete filaggrin thiab loricrin, thiab upregulating cov kev qhia ntawm nruj junction proteins claudin-1 thiab occludin.
Qhov no ua tau zoo ntxiv dag zog rau cov qauv kev ntseeg siab ntawm cov dermal thiab epidermal hlwb, txhim kho daim tawv nqaij moisturizing muaj nuj nqi, thiab ua rau stratum corneum ntxiv lawm.
4.Antioxidant thiab Post-Procedure Kho
Cysteine residues muab cov pab pawg sulfhydryl rov ua dua tshiab uas pub electrons rau cov dawb radicals, scavenging reactive oxygen hom.
Ntawm txoj kev Nrf2/ARE, nws induces kev qhia ntawm ntau yam antioxidant enzymes (HO-1, SOD 2, GCLC); thaiv cov lipid peroxidation saw cov tshuaj tiv thaiv nyob rau hauv ntau hom kev puas tsuaj ntawm daim tawv nqaij.
Cov kev tshawb fawb soj ntsuam tau pom tias txo qis ntawm daim tawv nqaij pigmentation (kwv yees 12%) thiab nce nyob rau hauv radiance tom qab tas li 8 siv lub lim tiam.
Cysteine nws tus kheej tsim ib ntus occlusive gels nrog dawb aldehydes tam sim no ntawm qhov txhab, ceev sealing microchannels thiab yog li shortening lub inflammatory voj voog.
Upregulation ntawm VEGF thiab TGF-β3 txhawb nqa granulation ntaub so ntswg tsim, thaum lub scarfibrotic TGF-β1 signaling kuj inhibited.
COA
HPLC
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