Peptide CRO Advantage
Classis 100 sterile laboratory
Organic Chemistry Specialist
Available in mg-kg grade
Purity from crude to 99%
Multi-modal study routes
Peptide CRO Core Services
Technology development; process mapping.
Design and Synthesis
Customized peptide synthesis
Synthesize peptides of specific sequences (e.g*. linear peptides, cyclica peptides, modified peptides, etc.) according to customer requirements.
Modificationis genera
phosphorylation, acetylation, biotin labeling, Fluorescent labeling (FITC, Cy series), PEGylation, etc.
Special structural peptides
disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (CPP), glycosylated peptides, etc.
Peptide library construction
Provide combinatorial peptide libraries (e.g*. phage display libraries, solid phase synthesis libraries) for high throughput screening.
Process Development
Route design
Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (plerumque ≤50 amino acida), need to select protection group strategy, copulatione reagentia, etc.
Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (e.g*. E. coli, fermentum) and culture conditions..
Process optimization
Synthesis/expression optimization: increase yield (e.g*. temperatus, pH*, catalyst concentration).
Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.
Impurity control: remove missing peptides, mismatched sequences, oxidatio products, etc. to ensure purity (plerumque >98%).
Delivery support and technical assurance
Strict standards are enforced at every step of the process
Technology
Core Assurance
- aseptic laboratory
- nitrogen protection
- Per-step testing
- Organic Chemistry Specialist
Orders
Included Services
- HPLC;MS;Ph Reports
- Free desalting and transsalting
- Optional dissolution testing
- Optional endotoxin testing
Medicamine Peptides
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