Egregie,Argireline quoque nota quod Acetyl Hexapeptide-8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2) et acetyl hexapeptide 3
Speciatim,Argireline est synthetica peptide cuius series derivatur a N-terminus regione Snap-25 dapibus.
Fere,Argireline similis mechanism actionis ad botulinum toxin(Botox in utrem), assequendum anti-canus ac reducing rugae effectus inhibendo emissione neurotransmitter apud " neuromuscular divortia. Ut medicamine bioactive peptide,studia clinica ostendimus Argirelineam cutem rugam profunditatem reducere posse, amplio cutis elasticitates, et auget deponunt.
Sequentia
Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
CAS Number
616204-22-9
Formulae hypotheticae
C34H60N14O12S
M. Pondus
889 g / mol
1.Quid est Argireline?
Argireline evoluta est quasi breakthrough thema alternativa ad botulinum toxin. tamen, dissimilis botulinum toxin (“Botox in utrem”), quod requirit telae iniectio, Argireline operatur in applicatione ad thema epidermis, hoc metus consociata cum telae injectiones.
In suo core, Argireline intermiscetur the neurotransmitter dimittis a targeting the INCAENDO complexu (solutum NSF affectum dapibus receptor),quae est necessaria docking acetylcholine vesicles.Through quibus haec mechanism, laqueum formationis et stabilitatis implicat, ita inhibuit neurotransmitter emissio.
Aedificationem in hac mechanism, notabiliter, phisici Argireline in N-termini structuram SnAP-25 protein expresserunt . Certat cum SNAP-25 pro ligatura vesiculae-consociata membrana interdum (VAMP/sinaptobrevin).Haec peptide technicae formationem laquei complexu dissolvit, ita inhibentes neuronal exocytosis [1].
2.Argireline Benefits：
Argireline offert tolerantiam bonam et non-invasiveness.Specifically,pelagus beneficia includit:
(1).Reductio faciei musculi contractionis
Argireline regit speciem locutionis lineae(rugae frontis et pedes corvi) inhibendo acetylcholine release in exocytosis, quod prohibet musculus contractionem. Exempli gratia,Volumen Studiorum ostendimus 10% seri potest reducere argireline rugam profundum[2] by 30% post 30 diebus in vivo.
(2).Emendationem in Skin textura et levitas
Studia clinica ostenderunt applicando formulam continens 10% acetyl hexapeptide-8 ad vultus cutis cotidie for 20 dies potest leviter reducere cutis asperitatem et Regium transepidermalia aquarum detrimentum (TEWL) [3] .Ceterum,post 4 hebdomades, formula reducta rugam profunditatem 49% [4] .
(3).Cicatrix et Macula Emendatio
Aeque potius, in orci iudicii cum 26 cicatricem aegris, thema Argireline gel demonstratum:
- Cutis elasticitas in area tractata signanter augetur.
- Hydratationis gradus leviter minui
- Sebum productio in area cicatricis signanter diminuta est respectu regionis circumiacentis.
notissime, ante et post curationis imagines ostendit emendationem significantes cicatrices per interpellationes chirurgicas ad curatio cancer, CYSTA remotionem, aut mole remotionem.
3.conclusio
Collectively,Argireline est scientifice convalescit bioactive peptide cum manifesta mechanism actionis. Per viam actionis botulinum toxin imitando(“Botox in utrem”), posse applicare ea ratione,tuto et commode leniter relaxat musculus contractionem, efficaciter reducendo expressio lineae et meliori cute textura [5] .
COA
HPLC
MS
