ʻO Adipotide (FTPP a i ʻole proapototic peptide) he a peptidomimetic me ke kaʻina amino acid CKGGRAKDC-GG-D (KLAKLAK).
Ma muli o kona ʻano kikoʻī kikoʻī, hiki iā ia ke hoʻomaopopo pono a hoʻopaʻa i ʻelua mau mea loaʻa ma ka ʻili o nā kīʻaha koko i loko o ke kiko adipose: Hoʻohui A2 (ANXA2) a pāpā.
Hoʻoulu ia i ka vasoconstriction a me ka apoptosis hope i loko o kēia mau mea hoʻokipa; ke hooki nei na aa koko i ke koko, oxygen a me nā ʻano meaʻai ʻē aʻe i nā sela, make cell programmed ʻo ia ka hopena hope.
ʻO kēia mīkini pololei o ka hana ka mea i hoʻopili pololei ʻia ma ke kahua o ka pohō kaumaha.
ʻAʻole hoʻohālikelike nā ʻano like ʻole o ka glp-1 kuʻuna a i ʻole nā peptides pohō kaumaha waena.; adipocytes ʻo ia ka pahuhopu, ʻO ka apoptosis ke ala e hoʻemi ai i ke kaumaha.
Kaʻina
Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys-Gly-Gly-(dLys-dLeu-dAla-dLys-dLeu-dAla-dLys)2
Helu CAS
859216-15-2
ʻĀpana Molekala
C111H206N36O28S2
Kaumaha Molecular
2557.21
Noiʻi o Adipotide (FTTP)
1.Nā Lapaʻau Lapaʻau Hiki
Loaʻa i kāna mau noi – ʻano ʻano 2 diabetes, lapaau maʻi kanesa adjuvant, hoʻemi ʻia ka momona kūloko, maʻi ʻaʻai momona ʻole.
2.Lapaau o ke ano 2 ʻO ka maʻi maʻi a me ka momona
Ua hōʻike ʻia nā haʻawina kūʻokoʻa ma hope o ʻehiku mau lā o ka mālama ʻana me Adipotide obese ʻiole pākeke i hōʻike nui ʻia ka maikaʻi o ka naʻau o ka insulin., hoʻonui ʻia polysaccharide ka hoʻomanawanui a me ka emi ʻana o ka serum triglycerides.
ʻAʻole ʻo ke kaumaha ka mea mua, a i ʻole koke, hopena o ka lapaau.
ʻO An 8 Ua hōʻike ʻia ʻo Adipotide he mea lapaʻau maikaʻi loa no ka mālama ʻana i ka momona.
ʻO kahi ala kūʻokoʻa akā hōʻoia i ka mālama ʻana i ke ʻano 2 Ua wehe ʻia ka maʻi diabetes e kēia laina noiʻi.
3.Lapaau Adjuvant no ka ma'i ma'i
Hiki ke pōmaikaʻi nā poʻe maʻi maʻi maʻi ʻaʻai nui loa mai ka hōʻemi ʻana ʻiʻo adipose (ma o ka vasoconstriction a me ka apoptosis pololei) e hoʻomaikaʻi i nā mea a pau ma hope ka lāʻau lapaʻau nā hopena.
4.Hoemi Momona kūloko
ʻO ka hoʻemi ʻana i ka momona kūloko kahi ala i manaʻo ʻia o nā waiwai kūʻokoʻa o Adipotide.
Hōʻike ʻo Adipotide i kahi ala therapeutic kūikawā.
COA
HPLC
MS
