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Glycyl-L-Histidyl-L-Lysine, or GHK, is a tripeptide made up of glycine, հիստիդին, and lysine.

 

 

SKU: 198836 Կարգավիճակ:
Կիսեք ձեր սերը

Glycyl-L-Histidyl-L-Lysine, or GHK, is a tripeptide made up of գլիցին, հիստիդին, և լիզին. This peptide occurs naturally within the human body; blood plasma, saliva, and urine all contain it, with levels declining as part of the aging process. GHK binds to copper ions (Cu²⁺) to form a GHK-Cu complex. The complex itself activates various cellular signaling pathways; a broad spectrum of biological effects results from this activation.

Հերթականություն

Gly-His-Lys

CAS համարը

49557-75-7

Մոլեկուլային բանաձև

C14H24N6O4

Մոլեկուլային քաշը

340.38

Research Of GHK/Tripeptide-1

1.Versatile Biological Activities

GHK functions in both a signaling and carrier peptide capacity. Որպես ազդանշանային պեպտիդ, skin cells are prompted to produce increased amounts of էլաստին, պրոտեոգլիկաններ, գլիկոզամինոգլիկաններ, and ultimately collagen. The carrier aspect delivers the essential trace element copper directly to these cells.

These dual roles are responsible for the broad range of biological activities GHK exhibits – tissue repair being the prime example, along with հակաբորբոքային and notable հակաօքսիդանտ հատկությունները, potential anticancer effects, and distinct Regulation of gene expression.

2.Մաշկ Regeneration And Repair

Supporting skin regeneration is one of GHK’s most thoroughly documented effects. Studies confirm collagen (and specific գլիկոզամինոգլիկաններ/decorin) synthesis is stimulated. Regulation of key metalloproteinases (breakdown of the արտաբջջային մատրիցա being their primary function) and anti-proteases has also been demonstrated.

The previously mentioned dual action gives GHK a comprehensive regulatory effect on all aspects of skin protein breakdown; preventing both excessive accumulation of damaged proteins and complete degradation.

3.Հակաօքսիդանտ / Հակաբորբոքային Properties

Strong antioxidant and broad-spectrum anti-inflammatory capabilities are possessed by GHK. Harmful free radicals -ից lipid peroxidation are neutralized, կերատինոցիտներ specifically being protected from UV-induced damage. Complete blocking of the copper dependent oxidation of LDL(Low-Density Lipoprotein) is another clear example of this protective mechanism.

4.Gene Expression Regulation

GHK supports connective tissue repair and remodeling through gene expression. The reversal of the genetic signature of COPD(Chronic Obstructive Pulmonary Disease) is a significant line of research; 127 genes are implicated in the disease and GHK has been shown to restore them to a healthy state.

5.Molecular Mechanism Studies

Emerging research demonstrates that GHK can reset aberrant gene and protein expression, և UPS(Ubiquitin-Proteasome System) ֆունկցիան, toward a healthier state.

Anti-aging and health promotion, as a result of all of the above, is a highly desirable objective of GHK application.

Its therapeutic potential is therefore considerable.

COA

HPLC

MS

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10 մգ, 100 մգ, 50 մգ

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