ʻO Bronchogen kahi peptide pōkole bioactive i haku ʻia me ʻehā amino acids; he lālā o ka ʻohana peptides regulatory epigenetic. Hoʻomaka mua ʻia e kahi hui noiʻi ma ka Institute of Bioregulation and Gerontology ma St. Petersburg, Lukia, hoʻohana nui ia i nā hopena pale a hoʻoponopono i ka ʻiʻo māmā.
Hoʻoponopono i ka hōʻike gene a ma hope hoʻohui pūmua ʻo ia nā ʻano hana koʻikoʻi e hoʻopili ʻia ai kēia mau hopena.
Kaʻina
Ala-Glu-Asp-Leu
Helu CAS
/
ʻĀpana Molekala
C18H30N4O9
Kaumaha Molecular
446.45
Noi'i o Bronchogen Peptide
1.Chromatin-Hana ʻia ʻo Bronchogen i ka hoʻihoʻi ʻana i ka hana Pulmonary
Hōʻike nā haʻawina e pili pono ana ʻo Bronchogen i nā histones (H1, H2b, H3, ʻO H4 nā laʻana mua) a me DNA; epigenetic ʻO ka hoʻoponopono ʻana i nā genes pili i ka hana o ka māmā ka mea nui.
Ua hōʻike nā ʻano hoʻokolohua i nā hopena hoʻihoʻi – pneumonia maʻi bacteria, nā ʻano like ʻole o ka maʻi maʻi fibrosis puʻupuʻu, a me nā ʻano like ʻole o ka ʻeha o ka maʻi maʻi ʻawaʻawa.
ʻO ka hoʻomaikaʻi ʻana i ka morphology a me ka hana o nā cell epithelial bronchial kahi hopena kūlike o kēia lapaʻau.
ʻO ke ʻano o ka hana ponoʻī he multifaceted, ʻO ka hoʻoponopono epigenetic ke kia waena, ka hana cellular a me ka homeostasis kiko ma muli o ka hopena pololei.
2.Hoʻoponopono Hōʻike Gene: Nā hopena anti-inflammatory a me Anti-fibrotic
ʻO ka hoʻololi ʻana i ka hana transcriptional ka hana koʻikoʻi o Bronchogen.
Loaʻa ka hana preclinical a ke ʻike mau nei i nā ʻano genes i hoʻopili ʻia e ia.
Hoʻoponopono i nā mea transcription (a me nā genes marker) pili me ka alveolar epithelial differentiation ua palapala maikaʻi ʻia (NKX2-1, ʻO nā lālā o ka ʻohana FOX nā kumu hoʻohālike).
Hoʻopili pū ʻia nā protein huna e like me SCGB1A1/3A2.
Mālama ʻia ka paʻa o ka alveolus a me ka hana surfactant e kēia mau genes.
Nā genes pili i ka inflammatory (CD79A, NOS-3 inā mālama ka hoʻomanaʻo) ua hooponopono like – ʻO ka ʻeha nui a i ʻole ka mālama ʻole ʻia kahi hopena pathological nui o ka maʻi māmā, a ʻo ka Bronchogen ka mea e hoʻemi iki ai.
Ua kākoʻo maikaʻi ʻia nā hopena anti-inflammatory a me anti-fibrotic o Bronchogen i nā ʻano hoʻohālike.
3.ʻO ka hoʻonui a me ka hoʻokaʻawale ʻana
Hōʻike nā haʻawina i ka hoʻopili ʻana o Bronchogen i nā genes e pili ana i ka pōʻai cell a me ka apoptosis.
Kūkākūkā, hoʻololi ʻo ia i ka hōʻike ʻana o kahi moʻo hōʻailona hoʻonui cell, MKI67 (Ki67), a me nā ʻano gen anti-apoptotic like ʻole MCL1; ka gene suppressor tumor TP53 (p53) ʻo ia kekahi o nā laʻana i aʻo nui ʻia.
ʻO kēia hana hoʻoponopono e hoʻoikaika i ka hoʻoponopono ʻana i nā kiko ma hope o ka ʻeha, me ka hoʻopau ʻana i ka hoʻonui ʻia ʻana o nā cell abnormal i makemake ʻia he wahi hope⁵.
I kēia manawa, kūʻai nui ʻia ʻo Bronchogen ma ke ʻano he meaʻai meaʻai a i ʻole peptide bioregulator – he 'peptide complex no ka bronchopulmonary system’ inā makemake ʻoe.
ʻO ka lāʻau hoʻohui no ka bronchitis mau, ʻO ka maʻi pulmonary obstructive mau (COPD) a me ka bronchial hānō ʻo ia ka hoʻohana maʻamau; hoihoi hou ana (ma ka hapa iki) hana mucosal bronchial, ka hoʻomaikaʻi ʻana i ka hana pulmonary, ʻO ka hoʻonui ʻana i ka hana surfactant a ma hope o ka hoʻohuli ʻana i ka emi ʻana o nā makahiki like ʻole i ka hana o ka māmā ka mea i manaʻo ʻia no nā hopena..
Hoʻohui ʻia ka Bronchogen me nā peptides ʻē aʻe, ʻO ka hoʻihoʻi ʻana i ka hana o ka māmā ma hope o COVID-19 kahi wahi kikoʻī o ka hoihoi; ʻO ka hoʻoponopono ʻana o ka immune a me ka alveolar type e manaʻoʻiʻo ʻia e hoʻoponopono ʻia e ia.
Ke kali ʻia nei ka hōʻoia hōʻoia ʻana o nā mea hoʻohana āpau a me ka wā e hiki mai ana.
COA
HPLC
MS
