Acetyl Tetrapeptide-11 (Sunan alamar Syniorage™) peptide siginar roba ne. Bincike mai zurfi a cikin filin kayan shafawa ya mayar da hankali kan ikonsa na inganta nau'ikan alamun tsufa na fata.; elasticity, tsayin daka, da wani nau'i na annuri kasancewar wasu misalan da aka fi rubutawa.
Jeri
Ac-Pro-Pro-Tyr-Leu
Lambar CAS
928006-88-6
Tsarin kwayoyin halitta
Saukewa: C27H38N4O7
Nauyin Kwayoyin Halitta
530.6 g/mol
Binciken Acetyl Tetrapeptide-11
Babban aikin nazarin halittu na Acetyl Tetrapeptide-11 cibiyoyin kula da kuma a wasu lokuta gyara., daidaiton tsari da aiki na Dermal-Epidermal Junction (RUWA). Hanyoyi biyu na farko sune alhakin wannan tsarin aiki:
Ƙarfafa haɓakar keratinocyte: Keratinocytes sune epidermis da kansu. Yaɗuwar al'ada da bambance-bambancen na gaba duk abubuwan da ke tattare da shingen fata mai aiki da kyau, kwanciyar hankali na tsari, da kuma gyara kai sosai. A matsayin peptide mai sigina kai tsaye yana haɓaka ci gaban keratinocyte na epidermal, ƙãra yawan tantanin halitta kasancewar sakamako ɗaya ne wanda ake iya aunawa, sake farfadowa da sauri kasancewar ƙarshen sakamakon wannan tsari.
Inganta Glycoprotein Synthesis – musamman syndecan-1 kuma zuwa wani batu nau'in XVII collagen. Syndecan-1 (transmembrane heparan sulfate proteoglycan idan na tuna daidai) yana ɗaure ligands (kwayoyin adhesion cell, daban-daban girma dalilai) ta gefen sassan sa; mannewar intercellular da duk hulɗar microenvironmental an daidaita su. Nau'in XVII collagen yana kusa da muhimmin bangaren hemidesmosomes. Rage kiran ko dai, tare da tsufa, yana kaiwa ga bushewa, laxity da aka ambata a baya. Inganta aikin shinge da annuri duka fa'idodin tsari na biyu ne na Acetyl Tetrapeptide-11.
Ƙarin rahotannin kimiyya sun nuna kusan cikar toshe siginar watsa neuromuscular (ta hanyar hana masu karɓar SNARE), rage yawan sakin duka catecholamine da acetylcholine. Ana rage wrinkles masu ƙarfi ta wannan aikin kuma.
Nazarin asibiti sun tabbatar da cewa abubuwan da ke ɗauke da acetyl tetrapeptide-11 (misali, a a 3% maida hankali) muhimmanci ƙara duka fata kauri da ƙarfi. Ɗayan takamaiman gwajin inganci ya ƙunshi 19 mata masu aikin sa kai; Samfurin da ake tambaya shine kawai sashi mai aiki. Sakamako ya nuna karara, bambanci mai aunawa daga rukunin kula da wuribo – Abubuwan da ke amfani da acetyl tetrapeptide mai ɗauke da tsari sun fi girma, mafi m fata.
Wannan binciken yana goyan bayan 'fassara’ na daban-daban in vitro lura da nazarin halittu ayyuka zuwa na zahiri fata kyautata. Shaida ta tushen anti-tsufa shine abin da wannan sinadari ya tabbatar da kansa.
Saboda wannan musamman tsarin aiki, Acetyl Tetrapeptide-11 an haɗa shi da farko a cikin manyan samfuran kayan kwalliya na ƙarshen zamani.. Karfin fata, yawa (na iri daban-daban), kuma sassaukakin kwane-kwane duk an inganta shi.
peptides masu sigina suna aiki azaman kusa da cikakkiyar ƙwayoyin manzo; Ana haifar da martani mai ƙarfi amma takamaiman salon salula, ƙananan taro shine duk abin da ake buƙata. Babban ko kusa akai matakan peptide kanta ba a buƙata – sassa a kowace nau'in nau'in nau'in nau'in nau'in nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i sassa)..
COA
HPLC
MS
