Tetrapeptide-26 (sunan kasuwanci Chronogen®) tetrapeptide ne da aka ƙera ta hanyar haɓakar tsufa wanda aka haɗa ta hanyar zamani na zamani. ilmin halitta kwayoyin halitta, tare da ka'idodin ƙira da aka samo asali a fagen epigenetics.
Jerin amino acid ɗin sa shine H-Ser-Pro-Leu-Gln-NH2 kuma nauyin kwayoyin sa ya kai kusan 442.51 – 443.49 Dalton.
Gabaɗaya farin foda ne mai tsafta yawanci wuce gona da iri 95% ku 98%, kuma yana da kyakkyawan narkewar ruwa.
A matsayin aikin kwaskwarima an tsara shi musamman don tallafawa fata circadian rhythm, yana ba shi damar kare shi daga tasirin waje yayin rana da haɓaka haɓakawa a cikin dare.
Jeri
Ser-Pro-Leu-Gln-NH2
Lambar CAS
1234463-61-6
Tsarin kwayoyin halitta
Saukewa: C19H34N6O6
Nauyin Kwayoyin Halitta
442.51
Tetrapeptide-26 Bincike mai alaƙa
1.Babban Ra'ayi da Tsarin Aiki
Kamar yadda ɗayan sunayen kasuwancin Tetrapeptide-26 shine Chronogen®, suna da ke nuna tsakiyar tsarin aikinsa dangane da “lokaci” (Chrono) da ka'idojin kwayoyin halitta - yana aiki ta hanyar daidaita agogon circadian rhythm na fata wanda ke ba da gudummawa ga tasirin tsufa..
Kasancewa babban tsaftar peptide roba, yawanci ana haɗa shi a matakan ganowa a ciki formulations kuma dole ne a adana a ƙarƙashin sanyi, yanayin bushewa kuma an kiyaye shi daga haske don kiyaye kwanciyar hankali¹.
Ayyukan anti-tsufa na Tetrapeptide-26 ana samun su ba ta hanyar hanawa na al'ada ko kunna hanyoyin sigina ba amma ta hanyar ingantaccen tsarin tsarin epigenetic., da farko suna niyya agogon nazarin halittu na ciki na ƙwayoyin fata.
2.Kwayoyin Halitta na Circadian Rhythm Modulation
Tetrapeptide-26 yana taimakawa wajen dawo da ikon gyaran kai a duk tsawon daren dare ta hanyar kiyaye matakan bayyana ainihin kwayoyin circadian ciki har da. KYAUTA, BMAL1 kuma PER1, wadanda suka rushe da ultraviolet (UV) lalacewa.
3.Gyaran DNA Taimako
Wannan peptide yana haifar da ikon halitta na fata don gyara lalacewar DNA ta hanyar bayyanar UV (kamar su konewar sel) kuma yana ƙara haɓakar zaruruwan collagen a cikin fata don ingantaccen ƙarfi da ƙarfi ².
4.Anti-Photoaging
Tetrapeptide-26 yana rage alamun tsufa kamar wrinkles, layi mai kyau, da laxity na fata ta hanyar hana hanyoyin ƙwayoyin cuta masu alaƙa da daukar hoto.
Ana amfani da Tetrapeptide-26 da farko a cikin manyan kayan shafawa na rigakafin tsufa, kamar maganin dare da kuma ampoules, don yin amfani da iyakar aikin gyaran fata a lokacin barci, don haka inganta shigar sinadarai da inganci.
Ana yin shi akai-akai tare da sauran peptides (misali, Acetyl Tetrapeptide-9) ko kayan tsiro (misali, Albizia Julibrissin Bark Extract), inda suke aiki tare da juna don rage girman glycation-haifar da lalacewa da rage alamun gajiya, samar da cikakkiyar fa'idar hana tsufa ³.
Tetrapeptide-26 yana wakiltar wata sabuwar hanya a cikin rigakafin tsufa dangane da epigenetic da rhythms na circadian..
Babban amfaninsa shine cimma fata farfadowa ta hanyoyi da yawa (Gyaran DNA, tsarin rhythm, collagen kira).
Kodayake yawancin binciken an yi su a cikin vitro ko a matsayin gwaji na asibiti na farko, An riga an tabbatar da aikace-aikacen sa a cikin kayan kwalliya.
COA
HPLC
MS
