Acetyl Tripeptide-1 shine siginar gyara siginar peptide, Haɗa ta hanyar N-terminal acetylation ("capping" gyara) Trieptide GHK da ke faruwa a zahiri da aka samu a ciki plasma kuma yana da tsarin sinadarai mai kama da Acetylated Polypeptide-1. Wannan gyare-gyaren tsarin yana magance ƙalubalen da aka ambata na ainihin GHK, ciki har da rashin zaman lafiya saboda aminooxidases, rashin kunnawa a cikin kayan kwalliya, da gajeriyar rabin rayuwa.
a takaice, Acetyl Tripeptide-1 yadda ya kamata yana rage layi mai kyau da wrinkles, tightens fata, da kuma tace fata. Abu ne mai hana tsufa tare da ingantaccen tsarin aiki, high takamaiman, da kuma nuna inganci.
Jeri
Ac-Gly-His-Lys-OH
Lambar CAS
350595-76-5
Tsarin kwayoyin halitta
Saukewa: C16H26N6O5
Nauyin Kwayoyin Halitta
382.42
Acetyl Tripeptide-1 Bincike mai alaƙa
1.Mahimman Hanyoyi da Tasirin Fuskoki da yawa
Abubuwan nunin acetylated GHK sun karu hydrophobicity da tsawon rabin rayuwa yayin da ake kiyaye Cu²⁺ mai jujjuyawa-chelation kaddarorin. Waɗannan kaddarorin suna sauƙaƙe samuwar rukunin gidajen jan ƙarfe-peptide a cikin Layer na dermal, inganta inganci ba tare da karuwa ba cytotoxicity.
Yana aiki akan dermal fibroblast sel don magance tsufa waɗanda ke haifar da abubuwan zamani ko muhalli. Ta hanyar ɗaure zuwa takamaiman masu karɓar saman tantanin halitta, yana kunna manyan siginar sigina na ciki don daidaita aikin salula a matakin kwayoyin halitta.
Yana ƙarfafa haɓakawa da ɓoyewar Nau'in I & III collagen da elastin, haifar da denser, kauri fata. Wannan, bi da bi, yana rage wrinkles, sagging, da kuma hollowing lalacewa ta hanyar collagen asarar.
Hakanan yana hana wuce haddi matrix metalloproteinase aiki, kafa microenvironment na fata mai karewa wanda ke rage lalata matrix na waje.
2.Yana inganta Collagen da Elastin Synthesis
Acetyl Tripeptide-1 ya kai dermal Layer na fata, inda yake aiki kamar a ligand don takamaiman masu karɓa a kan membrane cell fibroblast. Wannan ɗaurin yana kunnawa furotin da ke kunna mitogen (MAPK) kuma phosphoinotide 3-kinase (PI3K) hanyoyin sigina, inganta haɓakar fibroblast da haɓakawa anabolic metabolism.
A cikin na rubutawa matakin, yana haɓaka magana da haɗin nau'in collagen na Type I, Nau'in III collagen, kuma elastin, ta haka ne suke kara maida hankali da yawa a cikin dermis. Wannan yana haifar da plumper, mafi voluminized fata. ¹
3.Yana hana wuce gona da iri Matrix Metalloproteinase Magana
Acetyl Tripeptide-1 yana daidaita siginar salula don iyakance yawan haɓakar matrix metalloproteinases. (MMPs), yayin da kuma rage ci gaba extracellular matrix lalacewa ta hanyar danne kirarsu a matakin rubutu.
Kiyaye collagen da ke wanzu ta wannan hanyar yana taimakawa kiyaye kauri da amincin fata, yana ƙara lokacin canzawar collagen, don haka yana taimakawa wajen jinkirta tsarin tsufa. ²,³
4.Yana Haɓaka Aikin Gyaran Fatar salula
Acetyl Tripeptide-1 yana kunna hanyar PI3K/Akt, mabuɗin mai kula da rayuwar salula, girma, da kuma metabolism. Wannan haɓaka yana haɓaka ayyukan fibroblast kuma yana haɓaka gyaran microtrauma na yau da kullun.
Hakanan yana kawar da radicals kyauta da aka samar ta hanyar catalysis na karfe-ion, ta haka a kaikaice hana oxidative danniya-haifar da lalacewar salula da inganta lafiyar fata. ⁴
COA
HPLC
MS
