Caprooyl tetrapeptide-3 (Caprooyl-Gly-His-Lys-Lys) mai iko ne girma factor mimetic, ana amfani da shi sosai a cikin samfuran kwaskwarima don rigakafin wrinkle, tabbatarwa, bayan tiyata, da rigakafin mikewa.
Yana tsaye a matsayin daya daga cikin rare RUWA (Dermal-Epidermal Junction)-niyya peptides a cikin arsenal anti-tsufa na yanzu wanda ya haɗu da babban aiki, na kwarai kwanciyar hankali, da ƙananan haushi.
Ana haɓaka wannan peptide ta hanyar simulation da ingantawa na GHK, guntun waraka da aka samu daga Canji Factor Growth. Yayin da GHK na halitta yana haɓaka haɓakawa da kunnawa Collagen VII, Laminin-5, kuma Fibronectin, aikace-aikacen sa na asibiti yana iyakance ta gajeriyar rabin rayuwar plasma da ƙarancin riƙewar fata.
Na musamman N-terminal ε-amino hexanoic acid acylation a cikin caprooyl tetrapeptide-3 yana haɓaka dacewa da ɗan adam. stratum corneum lipids ta ninki 6, yana haɓaka mahimmin bayanin furotin, yana kara karfin fata da ninki hudu, kuma yana inganta ilimin halitta sosai watsa sigina, don haka shawo kan iyakoki na asali na GHK na halitta a matsayin mai aiki na Topical.
The biomimetic, Tsarin gyaran dabi'a na caprooyl tetrapeptide-3 ya haifar da karɓuwarsa a cikin manyan kayan kwalliya kuma ya haɓaka ci gaba sosai a cikin binciken inganta wrinkle.1
Jeri
Caprooyl-Gly-His-Lys-Lys
Lambar CAS
1012317-71-3
Tsarin kwayoyin halitta
Saukewa: C32H59N9O11
Nauyin Kwayoyin Halitta
745.86
Caprooyl Tetrapeptide-3 Bincike mai alaƙa
1.Mahimman Dabaru da Ƙwarewar Multidimensional
Bugu da kari, Tsarinsa na musamman na biomimetic yana ba da damar masu yawan niyya, synergistic anti-tsufa da kwaskwarima amfanin. Yana riƙe ainihin aikin GHK-Cu peptide na ƙarshe, yana motsa kira da taro na Type I, III, da IV collagen da fibronectin, yayin da a lokaci guda hana overexpression na matrix metalloproteinase.
Wannan yana haifar da haɓaka mai mahimmanci a yanayin fata kuma yana haɓaka bayyanar ƙuruciya mai ɗorewa. Bugu da kari, shi upregulates kira na ginshiki membrane yankin sunadaran, ƙarfafa kwanciyar hankali na DEJ da haɓaka ƙarfin fata gaba ɗaya da haƙuri.
2.Ƙaddamar da Ayyukan Ƙirƙirar Ƙwararrun Ƙwararru
Caprooyl tetrapeptide-3 yana riƙe da ainihin jerin abubuwan GHK peptide., kyale shi da inganci chelate jan karfe ions (Ku) da kuma samar da hadadden hadaddun ayyuka a cikin jiki.
Wannan, bi da bi, yana daidaita ayyukan kwafi na kwayoyin halitta masu alaƙa da collagen a cikin sel, yana ƙarfafa haɗin nau'in I da Type III collagen.
Yana iya ƙara ƙara yawan ƙwayar collagen da kauri a cikin dermis, inganta yawan fata da kuma rage layukan layi da wrinkles da ke haifar da asarar collagen.
A cikin aikin asibiti, An nuna amfani da caprooyl tetrapeptide-3 na dogon lokaci don inganta ci gaban wrinkles kamar nasolabial folds da crow’s feet.2
3.Hana Ƙarfafa Matrix Metalloproteinase Kunnawa
Caprooyl tetrapeptide-3 yana hana overactivation na matrix metalloproteinases wanda ke haifar da damuwa kamar bayyanar UV..
A matakin kwayoyin halitta, yana tsoma baki tare da hanyoyin watsa sigina na al'ada, downregulating kira da kunna interstitial collagenase da gelatin.
Wannan yana ba da kariya mafi girma don mutunci da kwanciyar hankali na fata mai wanzuwa extracellular matrix tsari, don haka tsawaita lokacin bayyanar fata na ƙuruciya da kuma ja da baya da tsarin tsufa na fata a cikin mutane balagagge. 3
4.Ƙarfafa Haɗin Kwayoyin dermal-Epidermal da Ayyukan Kaya
Caprooyl tetrapeptide-3 yana haɓaka haɓakawa da kunna nau'in collagen Type IV, laminin, da kuma nau'in XVII collagen.
Wannan yana ƙarfafa junction dermal-epidermal, yana haɓaka ingantaccen musayar abinci mai gina jiki tsakanin ƙwayoyin dermal da epidermal, kuma yana haɓaka haɗin haɗin gwiwar hannu.
Sakamakon haka, yana inganta tsarin tallafi na ciki na fata, yana haifar da cikawa, karin juriya na rubutu.
Gabaɗaya, yana inganta aikin shingen fata, yana rage asarar danshi, kuma yana inganta haƙurin fata.
COA
HPLC
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