Pancragen wani peptide roba ne mai bioactive wanda ya ƙunshi amino acid guda huɗu.
Bincike kan aikin pancreatic ya sa masana kimiyya su gano a hormone-kamar kayan aiki mai aiki a cikin tsantsar pancreatic; stimulating da pancreas kanta kasancewa na farko lura sakamako.
Da farko dai ba a san ainihin abin da ke cikin wannan hormone ba.
Ci gaba a cikin ilmin halitta kwayoyin halitta kuma daga baya fasahar hada-hadar peptide ta ba da izinin yin kwafinta daidai – ci gaba da ingantawa da gyare-gyaren da aka yi niyya na ɓangarorin ɓangarorin asali daga asalin abin da aka samo asali shine hanyar da aka haɗa Pancragen..
Bayan kira, muhimmancin bincike na asibiti an danganta shi da shi.
Inganta kwanciyar hankali na nama na pancreatic, inganta gyara, da daidaita metabolism homeostasis sune fa'idodin farko da aka rubuta sosai.
Fadi anti-mai kumburi kuma ana ganin tasirin kariya a cikin hanta, koda, tsarin juyayi da sauran gabobin.
Jeri
H2N-Lys-Glu-Asp-Trp-OH
Lambar CAS
/
Tsarin kwayoyin halitta
Saukewa: C26H36N6O9
Nauyin Kwayoyin Halitta
576.607
Binciken Pancragen Peptide
1.Kariya da farfadowa na Pancreatic β-Cell
Ragewar waɗannan ƙwayoyin cuta shine ainihin abin da ke haifar da cututtuka ciwon sukari.
Kwaikwayi abubuwan haɓaka na ƙarshe ko alamun rayuwa, hana apoptosis wata hanya ce mai mahimmanci; kariya (aƙalla na ɗan lokaci) Kwayoyin beta da ƙirƙirar microenvironment mai tallafi don sabunta tantanin halitta.
Ana kiyaye matakan glucose na jini mai ƙarfi, a kaikaice ta hanyar ingantattun nama insulin sensitivity – rage sassa daban-daban na juriya na insulin da haɓakawa aikin mitochondrial.
Pancragen yana kunna waɗancan hanyoyin tsira da aka ambata a baya (PI3K/Dokar kuma MAPK/ERK).
Ƙaddamar da hanyoyin apoptotic a ƙarƙashin harin kumburi an yi nasarar hana su.
Gwaje-gwaje na asibiti a halin yanzu suna binciken farfadowar salon salula na gaskiya a matsayin ƙarshen ƙarshen.
Ƙarfafa rarrabuwa da yaɗuwar aƙalla wasu sel, haɗe da ƙaramin mahalli da aka ambata a baya, yana wakiltar babban koma baya na ci gaban ciwon sukari.
2.Tsarin Metabolic (kamar yadda a sama)
Ana ganin haɓakar tsarin ji na insulin a cikin ƙirar dabba.
Cytoprotection yana rage ciwon hanta da adipose nama na kullum kumburi.
Tasirin kai tsaye da kaikaice akan mai karɓar insulin da ayyukan sufuri duk wani bangare ne na ci gaban gabaɗayan haɓakar insulin.
Antioxidant da tasirin anti-mai kumburi na Pancragen yana da ƙimar bincike mai mahimmanci.
Neuropathy da kuma metabolism ciwo nau'in lalacewa, ko wata cuta da ke da alaka da ita oxidative danniya, iya kuma ya kamata a amfana daga aikace-aikacen warkewa na Pancragen.
COA
HPLC
MS
