Thymalin(Thymulin) polypeptide bioactive ne wanda ke ɓoye ta thymus nama; samu daga tsantsa daga wannan nama kanta. Yana aiki daidai da niyya da yawa don tsarawa da haɓaka fannoni daban-daban na rigakafi na salula aiki a cikin jiki. Yana motsa jiki ba tare da bata lokaci ba T lymphocyte balaga, lymphokine samarwa, halitta kisa cell aiki, kuma ta haka yake ƙarfafawa kula da rigakafi, tsaro, da ayyukan sharewa.
A asibiti, an nuna shi don magance nau'i daban-daban na rashin ƙarfi na rigakafi – nahaihu zama babban misali, da kuma chemotherapy-induced Rashin aiki na T-cell. Mahimman ci gaba a cikin marasa lafiya’ ana lura da matakan rigakafi gaba ɗaya, bada tallafi na dogon lokaci. Juyawa masu alaƙa da shekaru thymic atrophy kuma faɗuwar aikin na gaba shima yana da kyau a rubuce; maido da aikin rigakafi shine sakamakon kai tsaye na wannan tsari. Ana iya ƙarfafa juriyar tsofaffi ta hanyar amfani da Thymalin.
Thymalin, a matsayin m peptide immunomodulatory, yana da ƙima mai mahimmanci don kiyaye homeostasis na rigakafi da lafiyar gaba ɗaya.
Jeri
Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH
Lambar CAS
79621-14-0
Tsarin kwayoyin halitta
Saukewa: C33H54N12O15
Nauyin Kwayoyin Halitta
858.864
Binciken Thymalin
1.Maganin Immunodeficiency
Abubuwan da aka samu daban-daban da nakasassu na haihuwa ana sarrafa su da kyau ta hanyar Thymalin. Kai tsaye mataki a kan T lymphocytes (da 'core’ kwayoyin rigakafi) shi ne tsakiyar wannan tasiri.
Marasa lafiya na chemotherapy na dogon lokaci suna nuna ingantaccen ingantaccen asibiti a duk sigogin rigakafin da za a iya aunawa. Ƙarfin tsaro, kuma zuwa babban darajar rayuwa, an inganta.
2.Ƙarfafa rigakafi a cikin Mutanen da suka tsufa
Thymus yana jure juzu'i mai mahimmanci a cikin mutane masu tsufa, wanda ke haifar da raguwar siginar hormone na thymic kuma sakamakon haka ya rage fitowar T-cell. Rage juriya ga cututtuka daban-daban na ƙwayoyin cuta yana da sakamako mai kyau.
A matsayin exogenous thymic siginar wakili, Thymalin yana kwaikwayi microenvironment na thymic na halitta. Ayyukan sel na epithelial na rayuwa mai ban sha'awa, Ana haɓaka ƙarni na T-cell kuma ana iya dawo da mafi yawan rubutun T-cell.
Haɓaka aikin rigakafi na mutum mai tsufa shine sakamako na farko; musamman sassan immunomodulatory suna taka muhimmiyar rawa wajen magance wasu matakan tsufa.
3.Ciwon daji Adjuvant Therapy
Thymalin yana aiki azaman maɗaukaki mai mahimmanci a cikin cikakkiyar maganin cutar kansa. Daidaita martanin rigakafi da yawa akan ƙwayoyin kansa shine ma'anar iyawarsa.
Ciwon kasusuwa daga ko dai rediyo- ko chemotherapy yana da tasiri sosai, sauƙaƙe saurin dawo da farin kwayar jini. CD8+ cytotoxic T cell aiki da CD4+ an inganta aikin, inganta rigakafi gaba ɗaya akan ciwace-ciwacen daji.
Hana ci gaba, maimaituwa, da kuma metastasis, Thymalin na iya aiki tare da hanyoyin kwantar da hankali na zamani – Rayuwa mai haƙuri da ingancin rayuwa suna da tasiri sosai.
A cikin maganin ciwon daji, tsawaita chemotherapy yana lalata aikin rigakafi na mai haƙuri, ƙara saurin kamuwa da cututtuka na biyu. Inganta ingancin rayuwar masu ciwon daji shine babban fa'ida da Thymalin ke bayarwa.
4.Gudanar da Cututtuka
Hakanan ana kula da cututtuka masu tsanani da na yau da kullun yadda ya kamata; inganta pathogen clearance, rage tsawon lokacin cuta da kuma hanzarta warkar da nama da suka lalace duk wani bangare ne na bayanin martabarsa..
5.Inganta Gyaran Nama da Farfaɗowa
Ayyukan asibiti sun nuna Thymalin don hanzarta warkarwa bayan tiyata, konewa, rauni, ciwon ciki, da dai sauransu., inganta warkar da ingancin, da rage tabo.
Upregulation na bambancin salon salula dalilai da hanyoyin haɓaka suna da alaƙa. Thymalin ya nuna wannan ƙarfin farfadowar salon salula mai ƙarfi.
COA
HPLC
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