Hexapeptide-10, ka kiia ake ranei ko SIKVAV/Serilesine, ko te wae mahi iti rawa atu kua wehea mai i te rohe ao o te laminina α1 mekameka. Ko nga mahi koiora tino nui te ahuatanga o tenei peptide.
Ko nga rangahau o mua kua whakaatuhia he nui ake piri pūtau-whakatairanga me, ki te whānuitanga nui, axonal tipu-whakaongaonga kaha ina whakaritea ki te laminin mau. Te whakamohiotanga motuhake me te whakahoahoatanga o nga momo rereke whakaurunga me etahi atu kaiwhakawhiwhi mata ko tetahi atu taonga matua; te whakatipu pūtau, wehewehenga, me te oranga katoa ka whai i nga hua tika.
I roto neuroscience, te kaha whakaora mo te whakatika i te kino ki te pokapu ranei pūnaha io peripheral he pai te tuhi. Ko te mara whakapaipai kua kite i te pikinga nui o tona rongonui.
Hexapeptide-10, hoatu ona neuromodulatory me te kaha ki te whakatika i te kiko, he mea tino nui o te whakapaipai me te dermatological pūtaiao.
He tino harikoa te kaihoko, ka whaia e te kaiwhakawhanake adipiscing. Hei kaiwhakawhanake whenua, te pouri, me te kaporeihana o nga taonga, he urunga pūmua.
Raupapa
H-Ser-Ile-Lys-Val-Ala-Val-OH
Tau CAS
146439-94-3
Tātai rāpoi
C28H53N7O8
Taumaha rāpoi
615.77
Hexapeptide-10 Rangahau e pa ana
1.Whakatika kiri me te Ture Homeostasis
Te taapiri nui, te whakarereketanga mata ranei o mea koiora me te Hexapeptide-10 ka taea te whakauru i te rereketanga o nga pūtau kakau, fibroblast/endothelial te tipu o te pūtau me te heke tika – na reira ka tere ake te whakaora i nga patunga kiri.
Whakaritenga tika o keratinocyte Ko te toenga o te whakatipu-rereketanga te mea e wehe ke ai; he whakaōrite te nui o te paparanga paparanga epidermal proliferation, te whakatairanga i te wehewehenga o te stratum corneum.
Kua pai ake te kaha o te hanga kiri me te tapatahi katoa, kakano te take matua. Nga huarahi tohu neural kei te whakarereketia hoki, te whakaiti i te aro o te kiri ki nga whakaongaonga o waho; kiri tairongo i roto i nga painga o nga mea katoa i runga ake nei.
2.Te whakahaere i te tipu o te keratinocyte me te rereketanga hei pupuri i te homeostasis kiri
Ko te Hexapeptide-10 e mahi tika ana ki nga pūtau epidermal, te whakataurite i to raatau tipu me te rereketanga o muri mai.
Te aukati i te rereketanga rerekee me te wehenga kore whakahaere i roto i te paparanga papa, ka whakatika ake i te whakaaturanga ira o nga pūmua e pa ana ki te rerekeetanga. Nga mate rerekee o te pukoro na te koroheketanga, ahotea taiao, Ko nga ahuatanga kiri motuhake ranei ka tino arohia.
He oti ake, kua hanga te arai tinana pakari; increased hydration of the skin is a direct result, smoother and refined complexion being the end point of this process.
3.Sensitive Skin Regulation and Relief of associated Itching/Discomfort
Interaction with receptors on sensory neurons is the key mechanism; modulating ion channels thereby regulates neural excitability.
Pro-inflammatory factor secretion is inhibited, and an elevated sensory threshold leads to significant reduction or elimination of burning, stinging, itching and tightness. Long term environmental stress tolerance is thereby maintained at this neural level.
4.Promoting Axonal Growth and Neural Repair
Specific neuronal surface receptors are the targets of Hexapeptide-10.
This triggers intracellular cascades (Focal Adhesion Kinase a Src family kinases) that activate downstream gene expression pathways for growth and differentiation. Cytoskeletal Ko te whakahiato pūmua me te whakatikatika i roto i te neuron ano.
Kua whakaatuhia e nga rangahau maaori koiora nga toki whakaora ki te whai i nga tuunga scaffold kua tautuhia, te whakapumau ano i te hononga ki nga kopa kua tohua. Ko te whakatikatika i te kiko neural me te kiri he hua tika o enei mahi.
COA
HPLC
MS
