Peptide CRO Advantage
Klasse 100 steriles Labor
Spezialist für organische Chemie
Erhältlich in der mg-kg-Klasse
Reinheit von roh bis 99%
Multi-modal study routes
Peptide CRO Core Services
Technology development; process mapping.
Design and Synthesis
Customized peptide synthesis
Synthesize peptides of specific sequences (z.B. linear peptides, cyclic peptides, modified peptides, usw.) according to customer requirements.
Modification types
Phosphorylierung, Acetylierung, biotin labeling, fluorescent labeling (FITC, Cy series), PEGylierung, usw.
Special structural peptides
disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (CPP), glycosylated peptides, usw.
Peptide library construction
Provide combinatorial peptide libraries (z.B. phage display libraries, solid phase synthesis libraries) for high throughput screening.
Process Development
Route design
Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (normalerweise ≤50 Aminosäuren), need to select protection group strategy, coupling reagents, usw.
Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (z.B. E. coli, yeast) and culture conditions..
Process optimization
Synthesis/expression optimization: increase yield (z.B. Temperatur, pH-Wert, catalyst concentration).
Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.
Impurity control: remove missing peptides, mismatched sequences, oxidation products, usw. to ensure purity (normalerweise >98%).
Lieferunterstützung und technische Sicherheit
In jedem Schritt des Prozesses werden strenge Standards durchgesetzt
Technologie
Kernsicherheit
- aseptisches Labor
- Stickstoffschutz
- Testen pro Schritt
- Spezialist für organische Chemie
Bestellungen
Inklusivleistungen
- HPLC;MS;Ph-Berichte
- Kostenloses Entsalzen und Umsalzen
- Optionaler Auflösungstest
- Optionaler Endotoxintest
Kosmetische Peptide
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