Peptide CRO Advantage
Classe 100 laboratoire stérile
Spécialiste en chimie organique
Disponible en mg-kg
Pureté du brut à 99%
Multi-modal study routes
Peptide CRO Core Services
Technology development; process mapping.
Design and Synthesis
Customized peptide synthesis
Synthesize peptides of specific sequences (par exemple. peptides linéaires, peptides cycliques, modified peptides, etc.) according to customer requirements.
Types de modifications
phosphorylation, acétylation, biotin labeling, fluorescent labeling (FITC, Cy series), PEGylation, etc..
Special structural peptides
disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (CPP), glycosylated peptides, etc..
Peptide library construction
Provide combinatorial peptide libraries (par exemple. phage display libraries, solid phase synthesis libraries) for high throughput screening.
Process Development
Route design
Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (généralement ≤50 acides aminés), need to select protection group strategy, réactifs de couplage, etc..
Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (par exemple. E. coli, levure) and culture conditions..
Process optimization
Synthesis/expression optimization: increase yield (par exemple. température, pH, catalyst concentration).
Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.
Contrôle des impuretés: remove missing peptides, mismatched sequences, produits d'oxydation, etc.. to ensure purity (généralement >98%).
Assistance à la livraison et assurance technique
Des normes strictes sont appliquées à chaque étape du processus
Technologie
Assurance de base
- laboratoire aseptique
- protection contre l'azote
- Test par étape
- Spécialiste en chimie organique
Ordres
Services inclus
- HPLC;MS;Rapports de doctorat
- Dessalage et transsalage gratuits
- Test de dissolution facultatif
- Tests d'endotoxines facultatifs
Peptides Cosmétiques
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