Peptide CRO Advantage
Sehlopha 100 laboratori e hloekisitsoeng
Setsebi sa Khemistri ea Likokoana-hloko
E fumaneha ka grade ea mg-kg
Bohloeki ho tloha ho tse tala ho ea ho 99%
Multi-modal study routes
Peptide CRO Core Services
Technology development; process mapping.
Design and Synthesis
Customized peptide synthesis
Synthesize peptides of specific sequences (mohlala. li-peptide tsa linear, li-peptide tsa cyclic, modified peptides, etc.) according to customer requirements.
Mefuta ea ho fetola
phosphorylation, acetylation, biotin labeling, ho ngola fluorescent (FITC, Cy series), PEGylation, etc.
Special structural peptides
disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (CPP), glycosylated peptides, etc.
Peptide library construction
Provide combinatorial peptide libraries (mohlala. phage display libraries, solid phase synthesis libraries) for high throughput screening.
Process Development
Route design
Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (hangata ≤50 li-amino acid), need to select protection group strategy, ho kopanya li-reagents, etc.
Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (mohlala. E. coli, tomoso) and culture conditions..
Process optimization
Synthesis/expression optimization: increase yield (mohlala. mocheso, pH, catalyst concentration).
Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.
Impurity control: remove missing peptides, mismatched sequences, lihlahisoa tsa oxidation, etc. to ensure purity (hangata >98%).
Ts'ehetso ea thomello le netefatso ea tekheniki
Litekanyetso tse thata li sebelisoa mohatong o mong le o mong oa ts'ebetso
Thekenoloji
Tiisetso ea mantlha
- laboratori ea aseptic
- tshireletso ya naetrojene
- Teko ka mohato
- Setsebi sa Khemistri ea Likokoana-hloko
Litaelo
Litšebeletso tse kenyelelitsoeng
- HPLC;MOF;Litlaleho tsa Ph
- Free desalting le transsalting
- Teko ea boikhethelo ea ho qhibiliha
- Teko ea boikhethelo ea endotoxin
Li-peptide tsa Cosmetic
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