Crystagen ke peptide ea bohlokoa e laolang likokoana-hloko e etselitsoeng ho ntlafatsa matla a ho laola 'mele.. Patlisiso e hlophisitsoeng ea thymus ts'ebetso le lintho tsa eona tsa lekunutu li lebisitse ho kopanngoeng ha eona ka moralo o entsoeng ka boomo haholo.
Ho tloha ho sibolloa, maemo a mangata, Ho bonts'itsoe bokhoni ba ho laola likokoana-hloko tse nang le lipakane tse ngata bakeng sa Crystagen. Ts'ebetso ea mantlha e itšetlehile haholo ka ho ntlafatsa le ka nepo likarolo tse fapaneng tsa ts'ebetso ea sesole sa 'mele.
Mokhoa oa ho itšireletsa mafung matla ka ho khetheha a tsoa taolong e ntle ea tse itseng T lymphocyte likaroloana – mothusi Th cell ho ba mohlala o ka sehloohong, hammoho le lisele tsa T tsa cytotoxic; stimulation ea bona ho ata, kenya tshebetsong, le secretion e latelang ea sehlahisoa limolek'hule ke karolo ea mantlha ea ts'ebetso ena.
B-sele tse amanang le tshebetso le humoral immune immune e boetse e fetotsoe, ka synergistically ho tlatsa karabelo ea 'mele ea ho itšireletsa mafung.
Ho etsisa limolek'hule tsa ho itšireletsa mafung ka boeona ke e 'ngoe ea mekhoa ea bohlokoa ea Crystagen; ligand-litšebelisano tsa mofuta oa li-receptor holim'a lisele tsa 'mele tsa ho itšireletsa mafung li qala litsela tsa intracellular.
Lithuto tse ling tsa kliniki li tlalehile phello e tobileng e khahlanong le ho ruruha, ho fokotsa mefuta e sa tšoaneng ea khatello ea 'mele ea ho itšireletsa mafung e senya' mele.
Normalization of microenvironmental states ke ntlha e lakatsehang ea ho qetela.
immunomodulation e matla (jwale le nakong e tlang) ke seo Crystalagen e ikemiselitseng ho se fihlela.
Tatelano
Glu-Asp-Pro
Nomoro ea CAS
/
Foromo ea limolek'hule
C14H21N3O8
Boima ba Molek'hule
359.335
Patlisiso ea Crystal Peptide
1.Ho laola li-lymphocyte
Ketso e tobileng ho cellular immune likarabo ke sepheo sa mantlha sa Crystal.
Kapele, ts'ebetso e sebetsang haholoanyane le mefuta e mengata ea phapang e nepahetseng ho lisele tsa T tse sebetsang hantle antigen ho kopana kaofela ke karolo ea ts'ebetso ena.
2.Modulation of (porokerama) sesupo sa mmele
Joalokaha ho boletsoe ka holimo, lintlha tsohle tse fetileng li lebisa ts'ebetsong e hlophisitsoeng ea tsamaiso ea 'mele ea ho itšireletsa mafung.
Lisele tsa 'mele tsa ho itšireletsa mafung li ka fetola' me li tla fetola boemo ba tsona ho latela Crystagen.
3.Tšireletso ea Lisele le Tlhokomelo ea Homeostatic
Crystalgen e fokotsa tšenyo ea khatello ea oxidative ka ho khetheha liseleng tsa 'mele.
Keketseho ea li-antioxidants tse fapaneng tsa intracellular (glutathione ho ba mohlala o ka sehloohong) ke mokhoa o ka sehloohong oa ts'ebetso ts'ebetsong ena.
Ka nako e le nngwe, thibelo ea apoptosis ea mitochondrial tsela – ka polelo e laoloang ea BCl-2 lelapa liprotheine – e bonoa; phokotso ea apoptosis ea lisele tsena ka kotloloho e lebisa linakong tse telele tsa ho phela le mamello e latelang ea ts'ebetso.
Ho boloka microenvironment e tsitsitseng ka har'a 'mele ke thepa e' ngoe ea bohlokoa e bontšoang ke Crystalgen.
Ho laola (le ho khutlisetsa) karolo e nepahetseng ea likaroloana tse fapaneng tsa lisele tsa 'mele tsa ho itšireletsa mafung ke hore na mesebetsi ena ea 'mele ea ho itšireletsa mafung e tsosolosoa joang: tebelo, tshireletso e mafolofolo, le mesebetsi ea ho hloekisa.
Kankere pheko e thusang ke e 'ngoe ea likopo tse lakatsehang tsa ho qetela tsa mohala ona oa ts'ireletso ea 'mele.
COA
HPLC
MOF
