Thymogen

Patlisiso ea Thymogen Peptide

1.Mokhoa oa Ts'ebetso

Ts'ebetso e sebetsang le e nepahetseng ka har'a ho ata le ts'ebetso e latelang ea ts'ebetso ea tsena li-lymphocyte ke e 'ngoe ea likarolo tsa eona tsa bohlokoa. Endogenous lihormone tsa thymic’ ts'ebetso ea bioloji e matlafatsoa ke Thymogen; ho kopana le mekgoa ya matshwao a tlase, peptide e khothalletsa motsoako le bonyane karolo e itseng ea secretion ea bohlokoa li-cytokine (IL-2 ho ba mohlala o ka sehloohong), le ho hlophisoa ha li-receptor tse phahameng tsa IL-2.

2.Likopo tsa Clinical

Tšebeliso ea kalafo ea meriana ea Thymogen e sebetsana ka kotloloho le matla a 'mele a antiviral le anti-intracellular pathogen.; tlhokomelo e ntlafetseng ea 'mele oa ho itšireletsa mafung le ho lokolloa ha lisele tse itseng tsa hlahala ke liphello tse peli tse lakatsehang.

Phokotso ea linomoro tse itseng tsa lisele tsa T kapa ho senyeha ha tšebetso ka mefuta e fapaneng immunodeficiency linaha li ka lokisoa. Ho tsosolosa Th1/Th2 tekanyo hape ke karolo ea bokhoni ba eona ba kliniki.

3.Tlhōlo ea T Lymphocyte

Ho phahamisa (le ho boloka) T lymphocyte ntshetsopele, phapang le likarolo tsohle tse amanang le kholo: Ho etsisa tlhaho ea tlhaho ea thymic microenvironment, Thymogen e sebetsa ka ho toba 'mokong’ sesole sa 'mele.

Ho tlama ka ho khetheha ho lisele tse shebiloeng tse lateloang ke pontšo ea intracellular ke hona ho tsamaisang ts'ebetso ena.

Mature T cell subsets ke sehlahisoa sa ho qetela, tloaelehileng letamo boholo le tshebetso ho ba loketseng qetellong boemo ba taolo 'mele o hloka.

Ho fokotseha ho amanang le botsofali ba 'mele ke e' ngoe ea liqholotso tsa bohlokoa tsa bongaka tseo Thymogen e fanang ka thuso ea 'nete le e ka lekanngoang..

4.Anti-infective Immunity

Ho matlafatsa karabelo ea 'mele ea ho itšireletsa mafung le matla a ho thibela tšoaetso: Thymogen e ntlafatsa haholo katleho ea karabelo ea 'mele ea' mele ea ho itšireletsa mafung.

Nakong ea tlhaselo ea pathogen, Thymogen e khothalletsa lisele tsa T ka matla hore li hlahise li-cytokine tsa bohlokoa tse fapaneng; tsepameng phagocytosis 'me ho bolaoa ha likokoana-hloko ka mor'a moo ho thusoa haholo ke lintlha tsena.

Tšebeliso ea meriana ea Thymogen e bontša ntlafatso e sebetsang ea tšireletso ea 'mele khahlanong le mafu a sa foleng le a tloaelehileng, ho khutsufatsa nako ea mafu a joalo, ho fokotsa kgafetsa ya ho ipheta; bakuli ba fokolisitsoeng ba ho itšireletsa mafung ba rua molemo haholo karolong ena ea ketso ea eona.

5.Adjunctive Anti-tumor Effects

Thymogen e ka ntlafatsa haholo Cytotoxic T cell /CTL ts'ebetso le ho ata, tsohle tse amanang le tlhahiso e khethehileng ea cytokine (IFN-γ ho ba mohlala o ka sehloohong).

Ho lemoha le ho felisa lisele tsa tumor ke karolo ea ts'ebetso ea mantlha ea sesole sa 'mele, ho lebela mmele ho ba lentsoe le nepahetseng haholoanyane le sebedisoang.

Kalafo ea radiotherapy le chemotherapy e senya tsamaiso ea mali le ea 'mele ea ho itšireletsa mafung ho isa bohōleng bo itseng; Ka mor'a phekolo ho senyeha ha 'mele oa ho itšireletsa mafung ke phello e ntle e tlalehiloeng hantle.

Tšebeliso ea thymogen moelelong ona e thusa 'mele oa mokuli hore o hlaphoheloe ts'ebetsong ea' mele ea ho itšireletsa mafung ho tsoa tšenyo e boletsoeng, mafu a tšoaetsanoang ka nako e le 'ngoe a fokotseha, boleng ba bophelo bo ntlafetse.