पेप्टाइड सीआरओ

Provide peptide technology exploration for pharmaceutical and biotechnology companies or research institutions; process development services.

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Peptide CRO Advantage

कक्षा 100 sterile laboratory

Organic Chemistry Specialist

Available in mg-kg grade

Purity from crude to 99%

Multi-modal study routes

Peptide CRO Core Services

Technology development; process mapping.

Design and Synthesis

Customized peptide synthesis

Synthesize peptides of specific sequences (उदाहरण के लिए:. linear peptides, cyclic peptides, modified peptides, वगैरह।) according to customer requirements.

Modification types

phosphorylation, acetylation, biotin labeling, fluorescent labeling (FITC, Cy series), पेगीलेशन, वगैरह.

Special structural peptides

disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (CPP), glycosylated peptides, वगैरह.

Peptide library construction

Provide combinatorial peptide libraries (उदाहरण के लिए:. phage display libraries, solid phase synthesis libraries) for high throughput screening.

Process Development

Route design

Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (usually ≤50 अमीनो अम्ल), need to select protection group strategy, coupling reagents, वगैरह.

Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (उदाहरण के लिए:. ई. coli, yeast) and culture conditions..

Process optimization

Synthesis/expression optimization: increase yield (उदाहरण के लिए:. तापमान, पीएच, catalyst concentration).

Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.

Impurity control: remove missing peptides, mismatched sequences, oxidation products, वगैरह. to ensure purity (usually >98%).

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