Nghọta ọhụrụ na imewe nke Bioactive Peptides na Chelating Agents maka Onyonyo na Therapy na Oncology

E mepụtala ọtụtụ peptides sịntetik maka nyocha na ọgwụgwọ ọrịa cancer mmadụ dabere na ikike ha nwere ilekwasị anya kpọmkwem ndị nabatara n'elu mkpụrụ ndụ kansa ma ọ bụ banye n'ime akpụkpọ ahụ sel.. Mgbanwe kemịkalụ nke agbụ amino acid emewo ka ọrụ ndụ dịkwuo mma, nkwụsi ike na ịdị irè nke peptide analogues na-arụ ọrụ ugbu a dị ka ọgwụ mgbochi ọrịa cancer ma ọ bụ dị ka ndị na-ahụ maka ihe ngosi ihe omimi.. Nkwụsi ike nke somatostatin, Integrins na bombesin analogues dị n'ahụ mmadụ amụbaala nke ukwuu site na cyclization na/ma ọ bụ ntinye nke amino acid na-abụghị eke na usoro peptide.. Ọzọkwa, N'ozuzu pharmacokinetic Njirimara nke ndị dị otú ahụ analogues na ndị ọzọ (gụnyere cholecystokinin, peptide intestinal vasoactive na neurotensin analogues) emelitere site na PEGylation na glycosylation. Ọzọkwa, njikọ nke analogues peptide ndị ahụ na ndị njikọ ọhụrụ na chelators bifunctional (dị ka AAZTA, ANT, Ọnyà, NOPO etc.), emepụtara moieties ndị akpọrọ redio nwere ọkara ndụ na-abawanye yana njikọ dị elu na ndị na-anabata cognate. Ntụleghachi a na-akọwa mgbanwe kemịkalụ kachasị mkpa na nso nso a ewebata na usoro amino acid yana ndị njikọ na ndị chelators bifunctional ọhụrụ nke megoro nke ọma nkọwapụta na uche nke peptides ejiri na nyocha na ọgwụgwọ oncologic..