Acetyl Tetrapeptide-3 bụ ihe sịntetik peptide biomimetic ihe mejupụtara amino acid anọ mejupụtara.
N'afọ ndị na-adịbeghị anya, ọ nwetara nlebara anya dị ukwuu dị ka ihe na-arụsi ọrụ ike n'ime ihe ịchọ mma na dermatology; ngwaahịa na-akwalite uto ntutu na ịgwọ ntutu isi bụ ihe atụ kachasị mma.
Usoro
Ac-Lys-Gly-His-Lys
Nọmba CAS
827306-88-7
Usoro ihe omimi
C22H38N8O6
Ibu molekụla
510.61 g/mol
Nnyocha nke Acetyl Tetrapeptide-3
Isi usoro a na-eme maka peptide a bụ ihe na-akpali akpali ozugbo ma ọ bụ na-apụtaghị ìhè dermal fibroblasts na dermal papilla cell (Ndị DPC) ka synthesize na nzuzo igodo Ụdị nke III collagen.
Ụdị nke III collagen n'onwe ya bụ ihe dị mkpa n'ụdị dị na oyi akwa akpụkpọ ahụ, njikọ anụ ahụ kpọmkwem gbara gburugburu ntutu isi – flexible structural support being the primary function attributed to it.
Following treatment with Acetyl Tetrapeptide-3, quantitative analysis showed a +65% increase in Type III collagen expression, laminin being another closely tracked marker (+285% mụbaa).
Type VII collagen forms the primary anchoring fibers, firmly linking the basement membrane to the dermis below.
Research has shown Acetyl Tetrapeptide-3 reversing cortisol-induced declines in this collagen type, thereby repairing and reinforcing the dermal-epidermal junction (MMIRI) nhazi.
Acetyl Tetrapeptide-3 enhances hair follicle adhesion to the scalp, while also promoting new follicle development.
In vitro and ex vivo studies have comprehensively validated the previously mentioned mechanism.
Nanoliposomes composed of copper peptides, Achọpụtara Acetyl Tetrapeptide-3 na myristoyl pentapeptide-4 iji kwalite uto ntutu site na ụzọ niile dị n'elu..
Ekwupụtala nrụpụta ụlọ ọgwụ.
A izu 24, randomized, Ọnwụnwa a na-achịkwa kpuru ìsì ugboro atọ tụnyere usoro ahịhịa (nwere Acetyl Tetrapeptide-3 dị ka akụkụ nke ihe ndị na-arụ ọrụ ya) ka 3% minoxidil, ma gosipụta ịdị irè ya na ọgwụgwọ androgenetic alopecia na profaịlụ nchekwa dị mma.
COA
HPLC
MS
