Tetrapeptide - 26 (aha ahia Chronogen®) bụ tetrapeptide na-egbochi ịka nká nke arụpụtarala site na nka ọgbara ọhụrụ. bayoloji ihe omimi, na ụkpụrụ imewe gbanyere mkpọrọgwụ n'ọhịa nke epigenetics.
Usoro amino acid ya bụ H-Ser-Pro-Leu-Gln-NH2 na ịdị arọ ya dị ihe dịka. 442.51 -443.49 Dalton.
Ọ na-abụkarị ntụ ntụ ọcha nwere ịdị ọcha na-adịkarị karịa 95% ka 98%, ma nwee ezigbo mmiri solubility.
Dị ka ihe ịchọ mma na-arụ ọrụ a na-emepụta ya kpọmkwem iji kwado akpụkpọ ahụ rhythm circadian, na-enyere ya aka ịgbachitere mmetụta ndị dị n'èzí n'ehihie ma kwalite ịmaliteghachi n'ime abalị.
Usoro
Ser-Pro-Leu-Gln-NH2
Nọmba CAS
1234463-61-6
Usoro ihe omimi
C19H34N6O6
Ibu molekụla
442.51
Nnyocha metụtara Tetrapeptide-26
1.Isi echiche na usoro nke ime ihe
Dịka otu n'ime aha azụmaahịa Tetrapeptide-26 bụ Chronogen®, aha na-egosi usoro ọrụ ya bụ isi n'ihe metụtara "oge" (Chrono) na usoro mkpụrụ ndụ ihe nketa-ọ na-eme site n'ịgbanwe elekere circadian rhythm akpụkpọ nke na-enye aka na mmetụta mgbochi ịka nká ya..
Ịbụ peptide sịntetik dị elu dị ọcha, a na-etinyekarị ya na ọkwa akara n'ime usoro na a ga-echekwara n'okpuru jụụ, ọnọdụ akọrọ ma chebe ya pụọ na ìhè iji kwado nkwụsi ike¹.
A na-enweta ọrụ mgbochi ịka nká nke Tetrapeptide-26 ọ bụghị site na mgbochi ma ọ bụ ịgbalite ụzọ mgbaàmà kama site na usoro nhazi usoro epigenetic dị nro., na-elekwasị anya na elekere ime n'ime ndụ nke mkpụrụ ndụ akpụkpọ ahụ.
2.Circadian Rhythm Genes Modulation
Tetrapeptide-26 na-enyere aka iweghachi ikike nrụzi onwe onye n'ime usoro abalị nke abalị site n'ịkwado ọkwa ngosipụta nke mkpụrụ ndụ ihe nketa circadian gụnyere. EGE, BMAL1 na PER1, nke na-akpaghasị ultraviolet (UV) mmebi.
3.Ndozi DNA Nkwado
Nke a peptide na-akpali ike anụ ahụ iji rụkwaa mmebi DNA nke mkpughe UV kpatara (dị ka mkpụrụ ndụ anwụ anwụ) ma na-abawanye njikọ nke eriri collagen n'ime akpụkpọ ahụ maka ngbanwe na nkwụsi ike ²..
4.Mgbochi foto
Tetrapeptide-26 na-ebelata ihe ịrịba ama nke ịka nká dị ka wrinkles, ahịrị ọma, and skin laxity by inhibiting molecular pathways related to ịse foto.
Tetrapeptide-26 is primarily used in high-end anti-ageing cosmetics, such as night serums and ampoules, to leverage the skin’s maximum repair activity during sleep, thereby enhancing ingredient penetration and efficacy.
It is frequently formulated together with other peptides (ọmụmaatụ, Acetyl Tetrapeptide-9) or plant extracts (eg., Albizia Julibrissin Bark Extract), where they synergistically work to minimize glycation-induced damage and reduce visible signs of fatigue, providing a comprehensive anti-ageing benefit ³.
Tetrapeptide-26 represents a novel approach in antiaging based on epigenetic and circadian rhythms.
Its greatest advantage is achieving skin rejuvenation through multi-target mechanisms (DNA repair, rhythm regulation, njikọ nke collagen).
Ọ bụ ezie na emerela ọtụtụ ọmụmụ ihe na vitro ma ọ bụ dị ka nnwale ụlọ ọgwụ izizi, Ngwa ya na ịchọ mma ka akwadolarị.
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