Peptide ọla kọpa GHK (GHK-Cu Peptide ma ọ bụ ọla kọpa Peptide) bụ ihe a kpụrụ n'onwe ya ígwè mgbagwoju n'etiti GHK tripeptide na ọla kọpa(II) ions. Nyocha X-ray na-egosi nke ahụ glycine na histidine Residues na-arụ ọrụ dị ka ligands na-ejikọta na cation metal (Ku²⁺). Agbụ akụkụ nke ihe fọdụrụ lysine nwere ike itinye aka n'ịmata ndị nabatara na sel akpụkpọ ahụ e lekwasịrị anya. ion ọla kọpa na-ekere òkè na usoro mgbochi ịka nká dị iche iche site na enzyme catalysis.Akụkụ abụọ nke GHK-Cu – GHK n'onwe ya na Cu2 – jide onwe ya, ma nkwado, ọrụ na igbochi usoro nke ịka nká.
Usoro
Gly-His-Lys-Cu
Nọmba CAS
89030-95-5
Usoro ihe omimi
C14H23CuN6O4
Ibu molekụla
401.91
Nnyocha nke GHK-CU / Peptide ọla kọpa GHK
Isi ihe dị iche n'etiti GHK na GHK-Cu sitere na GHK nwere nnukwu mmekọrịta maka ion ọla kọpa.. Mmekọrịta a pụtara na n'ime gburugburu ndụ nwere ion ọla kọpa, njide mmasị na-eme; na-eme ka mgbagwoju GHK-Cu kwụsiri ike. N'ikpeazụ, ọtụtụ ma ọ bụrụ na ọ bụghị ha niile, nke ọrụ ndu nke GHK na-arụ ọrụ site na ụdị ọla kọpa a.
1.Emelitere antioxidant na mgbochi mkpali Njirimara
Interleukin 6 (IL-6) bụ isi cytokine na-etinye aka na ya akpụkpọ mbufụt na ọgwụgwọ ọnya na-esote. GHK-Cu na-ebelata nzuzo nke cytokine a (kpaliri site na Ihe kpatara necrosis tumor / TNF-a). Na-eje ozi dị ka ihe ọzọ na corticosteroids ma ọ bụ omenala Topical ọgwụ mgbochi mkpali na-abụghị steroidal, ibelata mmetụta ndị nwere ike ịdị n'iji ogologo oge eme ihe bụ otu n'ime akụrụngwa ya bara uru karị.
2.Na-akwado njikọ mmezi anụ ahụ na nhazigharị
Glycosaminoglycans/GAG (hyaluronic acid ịbụ isi ihe atụ) kechie nnukwu mmiri, na-enye akpụkpọ ahụ ma hydration na njupụta nke ahụ dị mma dermal matrix na-enye.
Dị oke ala, Ọnụ ọgụgụ na-adịghị egbu egbu nke GHK-Cu na-akpali njikọ na mmebi nke GlycosAminoGlycans/GAGs na collagen.. Ọgwụgwọ ọnya, ụdị nile nke mmezi anụ ahụ, A na-emetụta udidi dị mma na nrịbawanye nke ọma.
3.Nlekọta akpụkpọ na mgbochi ịka nká
A na-etinye GHK-Cu ugbu a na serum, ude, ude anya wdg. Ọ na-enyere aka mee ka akpụkpọ ahụ sie ike, na-ebelata ahịrị ọma na wrinkles, mgbe radiance na ire ụtọ nke akpụkpọ na-niile opekempe eweghachi akụkụ. Ngwa ya dị ka ọgwụgwọ na-eduga n'ọganihu dị ịrịba ama na arụ ọrụ anụ ahụ.
4.Ebe nlekọta ntutu isi
A na-emepụta GHK-Cu dị ka ihe na-emepụta ntutu isi na ihe na-ewusi ike. Ntutu isi (ruo n'ókè ụfọdụ) enwere ike idozi ya site na ịkpali follicle na ịgbatị usoro anagen nke okirikiri. Nnyocha na-egosi ọkwa dị mma nke yiri minoxidil na usoro ndị a.
5.Na-akwalite Mmeghachi Neural (Neuroregeneration) na Nkọwapụta Gene
GHK-Cu bụ opekata mpe otu onye na-eweta mweghachi. Ọ na-emetụta ọtụtụ ọrịa ndị metụtara afọ. A na-eduzi ọmụmụ ụlọ ọgwụ na nke mbụ iji nwalee ihe niile dị n'elu, na ọgwụgwọ ụmụ mmadụ n'ọdịnihu nwere ike irite uru na nke a n'ezie, obere peptide molekul.
6.Nchịkọta
GHK-Cu bụ obere peptide nwere mmetụta physiological dị mkpa na ahụ mmadụ. A na-ejikarị ya eme ihe dị ka ntutu isi na ihe ịchọ mma, mana o doro anya na enwere ihe ngosi ụlọ ọgwụ ndị ọzọ.
Ikike nke itinye peptides eke jikọtara ya na ọla kọpa n'ime ọgwụgwọ nwere nnukwu nkwa maka imeziwanye nsonaazụ ndị ọrịa na mpaghara dịka njikwa ọrịa., ọgwụgwọ ọnya, uto ntutu, na cognitive ọrụ.
COA
HPLC
MS
