Oligopeptide-41 bụ peptide na-arụsi ọrụ ike nke ejiri n'ime ihe ịchọ mma na ngwaahịa nlekọta ntutu dị iche iche..
E sitere na simulation na njikarịcha nke β-ntutu isi Ọdịdị kpọmkwem ka keratinocyte ibu ihe(KGF), ọ lekwasịrị anya ntutu isi sel stem.
Nnukwu mmekọrita n'ihu FGFR2-IIIb a na-echekwa subunit, na mbelata dị ịrịba ama na cross-jide ka FGFR1; na-ebelata mitotic ahụ e kwuru n'elu “na-abụghị ntutu follicle” mmetụta na ịgbatị ọkara ndụ.
Mmetụta (itching, nkuchianaya pigmentation ịbụ isi ihe atụ) a na-ezere nke ukwuu.
Usoro
Ala-Ser-Ala-Lys-Trp-Thr-His-Asn-Gly-Gly-Glu-Met-Phe
Nọmba CAS
/
Usoro ihe omimi
C63H90N18O19S
Ibu molekụla
1435.58
Nnyocha metụtara Oligopeptide-41
1.Usoro nke Omume na arụmọrụ
Nnwale egosila peptide a na-arụ ọrụ ụzọ abụọ – β-catenin/Wnt na OTÚ-STAT5 – na ORSc stem cell; mweghachi nke okwu protein metụtara ya na ihe mgbochi apoptotic na-esote.
Ịgbatị oge uto nke ntutu isi bụ nsonaazụ kpọmkwem, A na-akwalite ọdịiche nke sel melanocyte, Ọnụnọ nke ntutu isi awọ belatara nke ukwuu.
A na-akwalite microcirculation mpaghara, ikike antioxidant nke melanocytes na-abawanye na ọkwa hydrogen peroxide belatara.
2.A na-enweta nrụpụta ugboro atọ
mgbochi nke ntutu isi, nkwalite nke ntutu isi na-arụ ọrụ, na-egbu oge ma ọ bụ kwụsị isi awọ kpamkpam.
3.Na-agbatị usoro Anagen
Ijikọ na ndị na-anabata FGFR2-IIIb n'elu sel follicular na-ebute dimerization nke nnabata na sochirinụ. phosphorylation.
Ụzọ Wnt/β-catenin na-arụ ọrụ, keratinocyte precursors na-anọgide na steeti azuokokoosisi, ọdịiche ọnụ egbuola oge.
Ex vivo Ụdị omenala ntutu isi mmadụ egosila mmụba doro anya na nke a na-ahụ anya na ma ogologo oge na njupụta nke usoro anagen..
4.Na-arụ ọrụ cell stem melanocyte na igbochi ntutu isi awọ
Pax3 na MITF-M A na-edozi okwu mkpụrụ ndụ ihe nketa.
A na-akwalite ọdịiche n'ime melanocytes tozuru okè.
Nnwale ụlọ ọgwụ na-akwado uru niile a kpọtụrụ aha na mbụ nke Oligopeptide-41.
A na-amụ ọrụ ndị ọzọ nke peptide, mana ha niile jikọtara ya na ụzọ akọwapụtara mbụ.
Mmetụta microcirculatory ọhụrụ na mgbochi mkpali na-emetụta ọdịnihu nke ntutu na ahụike anụ ahụ.
COA
HPLC
MS
