Palmitoyl Pentapeptide-4

Nnyocha nke Palmitoyl Pentapeptide-4

Palmitoyl Pentapeptide-4 bụ obere, peptide bioactive kpọmkwem. Na-ejikọta na mmalite ahụ (procollagen I), ụdị ọ bụla nke mkpali mpụga ọ na-enye na-eduga na nzaghachi cellular dị mma dị iche iche.

Elastin, fibronectin, glycosaminoglycans na collagen (I, III ịbụ ụdị kachasị mkpa, na IV kwukwara) na-akpali akpali; a na-akwado matrix extracellular, ọgwụgwọ ọnya bụ otu n'ime nsonaazụ ikpeazụ.

Njikọ collagen endogenous n'ime akpụkpọ ahụ n'onwe ya bụ ihe peptide bụ isi na-achọ inweta – mgbakwunye mpụga abụghị ebe njedebe, akara ekwentị bụ ihe a na-elekwasị anya.

Dị ka ezigbo molekul na-egosi, ntinye gafere stratum corneum bụ isi. Njide na cell elu receptors (kpọmkwem ụdị nke a ka na-akọwapụta ya) na-ebute ụzọ ndị a kpọtụrụ aha na mbụ.

Nkwalite mmepụta nke ụdị I/III collagen, opekempe akụkụ site na ụba procollagen, na njikọ hyaluronic acid, yana mmetụta mgbochi na MMP, na-eduga na mmụba ụgbụ na matriks dermal nke ndị ahịa na-ahụ ma na-erite uru na ya.

Palmitoyl Pentapeptide-4 na-arụ ọrụ dị ka ihe mkpali collagen; ime ka akpụkpọ ahụ dịkwuo mma, Nnụcha udidi gaa n'ọdịdị siri ike karị, na anya na-ebelata ezi ahịrị na wrinkles.

A 3% egosila itinye uche nke ihe a na-arụ ọrụ na ọ dị mma, na-adịghị ewe iwe, na enweghị mmetụta – adabara ụdị anụ ahụ niile.

A na-achịkwa placebo, Ọmụmụ kpuru ìsì abụọ lere anya kpọmkwem n'ụdị nwere Palmitoyl Pentapeptide-4 (0.005%) etinyere ugboro abụọ kwa ụbọchị n'akụkụ aka nri periorbital 28 ụbọchị.

Optical profilometry tụrụ mbelata dị iche iche: omimi nke wrinkle, ọkpụrụkpụ, na n'ókè nke nta siri ike; niile na-egosi mmụba dị ịrịba ama.

Ọmụmụ ihe abụọ ọzọ yiri nke ahụ (na-achịkwa placebo) kwadoro nsonaazụ ndị a, ụmụ nwanyị nwere nhụsianya periorbital a na-akpọkarị bụ ihe a na-elekwasị anya n'ọrụ ikpeazụ.

Onye kpuru ìsì abụọ, gbawara agbawa ihu, A na-eme nnwale a na-achịkwa placebo ka ọ tụlekwuo nke ọma ịdị irè ụlọ ọgwụ nke peptide, mma ahịrị/a wrinkle mma bụ isi ihe pụta.

Ọmụmụ ihe ọmụmụ ọnwa anọ a kpọtụrụ aha n'elu mere ka nchoputa gara aga sikwuo ike; Pal-KTTKS (ụdị na-arụ ọrụ nke peptide) gosiri ọganihu dị ịrịba ama na otutu parampat nke akpụkpọ ahụ, olu na omimi nke nhazi nke wrinkle.

Palmitoyl Pentapeptide-4 (Matrixyl) na-anọchi anya atụmatụ mgbochi ịka nká nke ọgbara ọhụrụ. Opekempe, peptide na-ahazi akara ngosi ekwentị; A na-eṅomi akara matriks endogenous.

Fibroblast arụ ọrụ sịntetik arụ ọrụ, ọtụtụ ECM (extracellular matriks) A na-emepụta ma na-echekwa ihe ndị mejupụtara ya, egbochiri mmebi.

Ntughari nhazi na ihe ịchọ mma bụ njedebe nke ọrụ a niile.