Palmitoyl Tripeptide-1(Pal-GHK/Palmitoyl-GHK) bụ mmepụta nke GHK.
Iji kemịkal na-agbanwe GHK palmitic acid – 16-carbon fatty acid – na-eme usoro a.
Acid palmitic na-ejikọta ya na peptide; na-eje ozi dị ka a hydrophobic oke, ebumnobi bụ isi bụ ịkwalite permeability anụ ahụ.
Usoro
Pal-Gly-His-Lys
Nọmba CAS
147732-56-7
Usoro ihe omimi
C30H54N6O5
Ibu molekụla
578.79 g/mol
Nnyocha nke Palmitoyl Tripeptide-1
GHK na-apụtakarị n'ime ahụ mmadụ, a na-ewerekwa ya dị ka bioregulator multifunctional.
Na-akpali akpali collagen na elastin njikọ, na-akwalite ọgwụgwọ ọnya, Mgbochi mkpali na mmetụta antioxidant bụ ihe niile sitere na ya.
Akpụkpọ anụ na-adịghị mma bụ isi ihe ịma aka GHK na-eche ihu mgbe ejiri ya dị ka ihe na-arụ ọrụ n'elu; obere peptides molekul site na okike bụ hydrophilic.
Ihe kachasị elu nke akpụkpọ ahụ, stratum corneum, na-emepụta ihe mgbochi hydrophobic nke ukwuu (lipids bụ isi mejupụtara).
A na-egbochi ntinye dị mma gafere oyi akwa a iji ruo saịtị ebumnuche dermal, ntinye bụ ihe na-egbochi ya.
Ịgbanwe peptides hydrophilic na ìgwè hydrophobic iji mee ka akpụkpọ ahụ dịkwuo mma bụ ngwọta ezi uche dị na ya.
Palmitoyl Tripeptide-1 bụ ngwaahịa nke atụmatụ a.
Covalent njikọ nke palmitic acid (fatty acid 16C zuru oke) ka GHK nweta nke a.
A na-ahụ ike nke anụ ahụ dị elu yana mma ndakọrịta na gburugburu lipid nke stratum corneum; Ọrụ ndu nke peptide n'onwe ya ka agbanwebeghị nke ukwuu, ebe a na-emeziwanye nnyefe transdermal.
Palmitoyl Tripeptide-1 n'onwe ya na-arụ ọrụ dị ka molekul na-egosi ike.
Ọ na-eṅomi akara ngosi eke emepụtara n'oge extracellular matriks (ECM) nkewa; na-emekọrịta ihe ozugbo na ndị na-anabata ya na membranes cell, ọ na-akpali akpali nke ukwuu collagen ụdị m njikọ.
N'otu oge, ọ na-akpali glycosaminoglycan (GAG) njikọ – akụkụ ọzọ dị mkpa n'usoro nke matriks akpụkpọ ahụ – na-amalite nrụzi na nhazi usoro.
N'ihi ya, Palmitoyl Tripeptide-1 gosipụtara ikike mgbochi ịka nká doro anya.
Nnyocha egosiwo kpọmkwem njikọ nke collagen na-akpali na omenala fibroblast mmadụ, mmebi nke collagen a (na-eso ogologo ebili mmiri UV) na-egbochi.
Palmitoyl Tripeptide-1 na analogues ya (Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, wdg.) A na-enyocha ya nke ọma ma tinye ya n'ọtụtụ usoro nlekọta anụ ahụ dị elu.
A na-eji Palmitoyl Tripeptide-1 eme ihe nke ọma na ihe ịchọ mma; Permeability akpụkpọ ahụ dị elu ma e jiri ya tụnyere GHK na ọrụ ndụ yiri ya bụ isi ihe kpatara nke a.
Matrixyl 3000™ bụ ezigbo atụ – Ihe abụọ na-arụ ọrụ bụ Palmitoyl Tripeptide-1 na tetrapeptide a kpọtụrụ aha na mbụ, ngwaahịa mgbochi ịka nká juru ebe niile na-eji nchikota a eme ihe.
Ugbu a enweghi ọmụmụ ụlọ ọgwụ onwe onye na-enyocha ịdị ọcha nke Palmitoyl Tripeptide-1..
Usoro mgbagwoju anya nwere ya na-abụkarị isiokwu nke nyocha ugbu a.
Ahịa na nnabata nke Palmitoyl Tripeptide-1 dị ka ihe ịchọ mma na-arụ ọrụ, Otú ọ dị, kwadoro nke ọma dị ka ihe ịchọ mma tozuru okè.
COA
HPLC
MS
