PTD-DBM

PTD-DBM is an acronym for Protein Transduction Domain (PTD)-Dvl Binding Motif (DBM).

Simply put, it is a follicular regeneration treatment. More specifically, it is a topical peptide-based scalp treatment that inhibits the follicle contraction effects of human hormones and enzymes, thereby effectively rescuing follicles at the stem cell level. Treatment with PTD-DBM both prevents hair loss and promotes the growth of new hair follicles.

Many researchers believe that intracellular WNT signaling pathways are responsible for follicle development and hair regrowth in humans. These pathways typically consist of proteins that communicate important cellular activity and growth signals to various cells in our body.

Descoberta do PTD-DBM

Professor Kang-Yeol Choi and a group of researchers at Yonsei University in South Korea have discovered a protein that causes hair loss in a condition known as androgenetic alopecia. This protein controls hair growth, and the researchers have developed a new substance that promotes hair regrowth by controlling the protein’s function.

A proteína responsável chama-se CXXC-type zinc finger protein 5 (CXXC5), que actua como um regulador negativo da via Wnt / β-catenina, associada ao crescimento do cabelo e à cicatrização de feridas. Quando o CXXC5 se liga a uma proteína chamada Disheveled, impede o desenvolvimento dos folículos e o crescimento do cabelo. Para aqueles de nós que querem manter o seu cabelo, isto não é bom. Este facto levou ao desenvolvimento de um novo bioquímico chamado PTD-DBM, que interfere com este processo de ligação.