Acetyl Dipeptide-1 cetyl ester

1.Acetyl Dipeptide-1 cetyl ester ke Eng?

Acetyl Dipeptide-1 Cetyl Ester ke peptide e entsoeng ka ho khetheha bakeng sa lihlahisoa tsa letlalo.; mosebetsi oa mantlha oa mantlha ke mofuta o itseng oa ho thoba letlalo, ho teneha le haufi le mefuta eohle ea phokotso ea ho ruruha.

Kholiso ea proopiomelanocortin (POMC) gene expression ke ketso ea eona ea bohlokoa e batlisisitsoeng. Ts'ebetso ea morao-rao ea POMC e lebisa ho li-peptide tse ngata tsa bioactive; melanin synthesis amanang le MSHs le hormone ea adrenocorticotropic (ACTH) ho ba mehlala e 'meli e meholo, ka β-endorphin (opoid e sebetsang) e boetse e hlahisoa.

α-MSH e tlama ho melanocyte melanocortin receptors, ho susumetsa bonyane karolo e itseng ea motsoako oa melanin, empa molao o boletsoeng pejana oa mosebetsi oa NF-κB o lumella ho ba le phello e tobileng e khahlanong le ho ruruha. Ho fokotsa Peptide e amanang le liphatsa tsa lefutso ea Calcitonin (CGRP) ho lokolloa ke ho qetela, leha ho le joalo e le ea bohlokoa, sehokelo sa neuro-soothing – CGRP ka boeona e sebetsa TRPV1 li-receptors.

Litlamorao tsohle tse kaholimo tsa bioloji ke tsona tse etsang hore acetyl dipeptide-1 cetyl ester e be ea bohlokoa indastering ea sejoale-joale ea litlolo.. Neuro-e thobang, litšitiso le litlamorao tse khahlanong le botsofali kaofela li fihlelleha ka mokhoa o amanang ka mekhoa ea ts'ebetso ea motsoako ona..

2.Liphuputso tsa Lipatlisiso Ka Acetyl Dipeptide-1 cetyl ester

1)Liphello tsa Neuro-soothing le Anti-inflammatory

Thutong e 'ngoe ea bongaka, 21 baithaopi ba ile ba ba le maikutlo a fokolang haholo a mocheso ka mor'a ho sebelisa tranelate e nang le 3% acetyl dipeptide-1 cetyl ester. Sekhahla se arohaneng sa thuto e sa boneng habeli 18 har'a baithaopi bana ba tlaleha maemo a phahameng a boiketlo ka kakaretso matsohong a ts'oeroeng ke sandpaper; tranelate e tšoanang e ne e le ho kenella.

Sena se fana ka maikutlo a hore acetyl dipeptide-1 cetearyl ester e kokobetsa bonyane mats'oenyeho a itseng a amanang le hypersensitive letlalo., tsamaiso ea methapo ea kutlo ho sebetsa ka ho fetelletseng e le taba ya mantlha.

Lithuto tsa in vitro li tiisa hore motsoako ka boeona oa fokotseha prostaglandin E2 (PGE2) sephiri – ho ruruha ha methapo ea kutlo ho ameha ka ho toba letlalong le bonolo. Ka nako e le nngwe, thibelo ea ntlha ea nyutlelie κB (NF-kB) pontsho tsela e bonoa.

NF-κB ke karolo ea bohlokoa ea ho ngola; li-cytokine tse ngata tsa pro-inflammatory (Interleukin-1 beta /IL-1β, Tumor necrosis factor/TNF,Interleukin 6 (IL-6) hara tse ding) li laoloa ka eona, 'me khatello ea eona e thibela ka katleho likarabo tsa ho ruruha.

2)Ho Matlafatsa Lekhalo la Letlalo

Patlisiso e bonts'a ts'ebetso ea liphatsa tsa lefutso tse fapaneng tse amanang le litšitiso ka sena se sebetsang, aquaporin 3 (AQP3), filaggrin (FLG), caspase 14 le keratin 10 ho ba har'a lintlafatso tse bonoang.

3)Lintho tse Khahlanong le Botsofali

Ho feta ho lokisoa ho thobang le ho bonolo, anti-botsofali e nang le litebello tse ngata ke phello ea boraro 'me mohlomong e lakatsehang ka ho fetisisa.

In vitro bonyane, Lintho tsa antioxidant le anti-glycation li bontšitsoe; tšenyo ea mahala ea radical le AGE liseleng tsa letlalo ke tsona tse tlatsetsang botsofaling.

UV photoaging ka ho khetheha e ka fokotsoa ke autophagy e boletsoeng pejana (cellular 'ho hloekisa') mekhoa, ka hona ho thusa ho boloka bophelo bo botle ba letlalo ka kakaretso le sebopeho.

3.Qetello

Acetyl Dipeptide-1 Cetearyl Ester e nahanisisitsoe hantle, skincare ea sejoale-joale e sebetsa ka mekhoa e mengata e hlalositsoeng le e hlahang ea ts'ebetso ho rarolla tse tloaelehileng, leha ho le joalo e le haufi-ufi, mathata a kajeno a letlalo.