Acetyl Tetrapeptide-2

Patlisiso ea Acetyl Tetrapeptide-2

1.Mokhoa oa Ts'ebetso: Phetoho ea Letšoao le Mosebetsi oa Motheo

E le pontšo ea peptide, Acetyl Tetrapeptide-2 e etselitsoe ho etsisa (ho isa tekanyong e kgolo) li-peptide tsa endogenous tsa motho.

Litaelo tse tobileng’ li isoa liseleng tsa letlalo; ho senyeha ha sebopeho se amanang le ts'ebetso ea botsofali ke seo e batlang ho se fetola.

Mosebetsi oa mantlha o boletsoeng ka holimo – botšepehi ba sebopeho le tšehetso e ntlafalitsoeng ea mochini bakeng sa dermis – ke morero oa eona o hlalosoang.

E bitsoa colloquially e le the “Gravity Peptide”, ho hanela ho fokotseha ho totobatsoa khafetsa e le e 'ngoe ea ts'ebeliso ea eona ea bohlokoa haholo.

2.Ho tsosolosa Letlalo Extracellular Matrix

Tšusumetso e kholo ea fibroblast synthesis ke seo Acetyl Tetrapeptide-2 e se fihlelang..

Mofuta oa I collagen e le protheine ea mantlha ea sebopeho, plumpness le thepa eohle e amanang le matla e ntlafatsoa.

Phuputso e ’ngoe e ile ea lekanyetsa phello – ho fihlela 47.3% ho ile ha hlokomeloa synthesis e eketsehileng.
Ho lumeloa hore ho phahama ha liphatsa tsa lefutso tse amanang le collagen ke karolo ea mokhoa oa eona.

Ho eketsa bongata bo felletseng ba (haufi ka ho sa feleng) collagen e fumanehang ke sepheo sa 'nete sa ho qetela; wrinkles le tsohle tse amanang le bokooa bo bobe, li fokotsehile.

3.Ho Khothalletsa Elastin Synthesis le Kopano e sebetsang

Lipatlisiso li tiisa hore Acetyl Tetrapeptide-2 e khothalletsa haholo tlhahiso ea elastin, ka keketseho e fihlang ho 21.7%.

Haholo-holo, e laola liphatsa tsa lefutso le litekanyetso tse latelang tsa protheine tsa liprotheine tse peli tse hlokahalang bakeng sa kopano e sebetsang ea elastic fiber – FBLN5 (Fibulin-5) le LOXL1(Lysyl oxidase homolog 1).

FBLN5 e sebetsa joalo ka “scaffold ea molek'hule,” ho tataisa tropoelastin e sa tsoa etsoa ho li-microfibrils bakeng sa ho beoa ho nepahetseng.

LOXL1, enzyme ea catalytic, e matlafatsa khokahano e hlokahalang lipakeng tsa melastin monomers; ho theha marang-rang a tsitsitseng a elastic fiber.

Taolo ea Synergistic ea lintlha tsena tse peli tsa bohlokoa ke seo Acetyl Tetrapeptide-2 e se fihlelang – ho eketsa bongata le kopano e sebetsang ea elastin.

Ho loantša matla a khoheli ka kotloloho, ntlafatso ea ho sisinyeha ha letlalo le botsoa ke litlamorao tse bonoang tsa ts'ebetso ena.

4.Liphello ho Keratinocyte Mechanical Properties

HaCaT lisele ke motho ea sa shoeng keratinocyte cell line e sebelisoang hangata liphuputsong tsa baeloji ea letlalo.

Kalafo ka peptide e fetola elasticity ea lisele tsena.

Ho eketsa ts'ebetso ea eona ho feta li-dermal fibroblasts tse bonolo, ho susumetsa thepa ea mochine bonyane karolo ea epidermis ke mokhoa o utloahalang le oa bohlokoa oa lipatlisiso. – ka kakaretso ho tiea ha letlalo ho ne ho tla rua molemo liphetohong tse joalo.

5.Lisebelisoa le Matla

Ka mekhoa e hlalositsoeng hantle ea ho thibela botsofali le mela e mengata ea lithuto tsa in vitro le tsa batho, Acetyl Tetrapeptide-2 e hlile e hlahile e le motsoako oa linaleli molemong oa ho hlokomela letlalo la sejoale-joale..

Ho tiisa le ho phahamisa ke tsona tse ka sehloohong, haufi le lits'ebetso tsa bokahohleng; litlolo, li-serum, lihlahisoa tsa molala le leha e le efe ‘defy gravity’ tlhahiso ea mofuta o tla lula e na le sena mantlha.
Collagen (le ho isa ntlha ea elastin) synthesis e boetse e ntlafatsoa, tsohle li lebisa ho tsosoloso e eketsehileng, boreledi, le letlalo le tsofetseng ka sebopeho sa sebopeho.

Thibelo e thibelang botsofali ke pheletso ea sebele ea tsena tsohle.