Acetyl Tetrapeptide-3 ke ntho ea maiketsetso biomimetic peptide e entsoeng ka masalla a amino acid.
Lilemong tsa morao tjena e fumane tlhokomelo e kholo e le motsoako o sebetsang ka har'a litlolo le dermatology; lihlahisoa tse khothalletsang kholo ea moriri le ho phekola tahlehelo ea moriri ke mehlala ea mantlha.
Tatelano
Ac-Lys-Gly-Hae-Ls
Nomoro ea CAS
827306-88-7
Foromo ea limolek'hule
C22H38N8O6
Boima ba Molek'hule
510.61 g/mol
Patlisiso ea Acetyl Tetrapeptide-3
Mokhoa oa mantlha oa ts'ebetso ea peptide ena ke ka ho toba kapa ka tsela e sa tobang e susumetsang dermal fibroblasts le lisele tsa dermal papilla (DPCs) ho kopanya le ho etsa senotlolo Mofuta oa III oa collagen.
Mofuta oa III oa collagen ka boeona ke boteng ba bohlokoa bo hlophisitsoeng ka har'a letlalo la letlalo, lithane tse kopanyang ka ho khetheha tse pota-potileng lesapo la moriri – flexible tshehetso ya sebopeho e le mosebetsi o ka sehloohong o bakwang ke ona.
Ho latela kalafo ka Acetyl Tetrapeptide-3, tlhahlobo ea lipalo e bonts'itse a +65% ho eketseha ha polelo ea collagen ea Mofuta oa III, lamin ke lesupa le leng le lateloang haholo (+285% nyollelo).
Mofuta VII collagen e etsa likhoele tsa mantlha tsa anchoring, ho kopanya ka thata lera la kamore e ka tlase ho dermis e ka tlase.
Lipatlisiso li bonts'itse Acetyl Tetrapeptide-3 e khutlisetsang ho fokotseha ho bakoang ke cortisol mofuteng ona oa collagen., ka hona ho lokisa le ho matlafatsa mateano a dermal-epidermal (METSI) sebopeho.
Acetyl Tetrapeptide-3 e matlafatsa moriri ho khomarela letlalo la hlooho, ha e ntse e khothaletsa nts'etsopele ea follicle e ncha.
Lithuto tsa in vitro le ex vivo li netefalitse ka botlalo mokhoa o boletsoeng pejana.
Nanoliposomes e entsoeng ka li-peptide tsa koporo, Acetyl Tetrapeptide-3 le myristoyl pentapeptide-4 li netefalitsoe ho khothaletsa kholo ea moriri ka litsela tsohle tse kaholimo..
Ts'ebetso ea bongaka e thehiloe.
A libeke tse 24, randomized, teko e laoloang ka makhetlo a mararo e bapisoa le ho etsoa ha litlama (e nang le Acetyl Tetrapeptide-3 e le karolo ea metsoako ea eona e sebetsang) ho 3% minoxidil, mme a bonts'a katleho e ts'oanang ea ho phekola alopecia ea androgenetic ka boemo bo botle ba polokeho.
COA
HPLC
MOF
