Acetyl Tetrapeptide-5 (e tsejoa e le Eyeseryl) ke peptide ea maiketsetso ea bioactive e sebelisoang haholo indastering ea litlolo. E etselitsoe ka ho khetheha ho sebetsana le mathata a fapaneng a letlalo a potolohileng mahlo, ke karolo ea motheo ea lihlahisoa tsa morao-rao tse thibelang botsofali. Sebopeho sa limolek'hule se na le tse 'nè masalla a amino acid, ka liphetoho tsa acetylation tse sebeletsang ho ntlafatsa ho kenella ha letlalo le botsitso ka kakaretso. Mekhoa e 'meli ea ts'ebetso e ikarabella bakeng sa liphello tsa eona tse bontšitsoeng; anti-wrinkle properties, phokotso ya ho ruruha ka tlasa mahlo, le ho fokotseha ho hoholo ha mefuta e itseng ea lidikadikwe tse lefifi. Bohlokoa ba eona bo tiisitsoeng lihlopheng tsena bo ngotsoe hantle.
Tatelano
Ac-β-Ala-His-Ser-His-OH
Nomoro ea CAS
820959-17-9
Foromo ea limolek'hule
C20H28N8O7
Boima ba Molek'hule
492.5 g/mol
Patlisiso ea Acetyl Tetrapeptide-5
1. Mokhoa oa Ts'ebetso: Multi-Targeted Efficacy
Ts'ebetso e felletseng ea Acetyl Tetrapeptide-5 e tsoa ho ts'ebetso ea eona e nang le lipheo tse ngata.. Ho ntlafatsa microcirculation le ho latela lymphatic drainage ke mekhoa ea pele e khetholloang; Thibelo ea collagen glycation e le mokhoa o utloisisoang haufinyane.
2. Mokhoa 1: Ho ntlafatsa Microcirculation le ho Fokotsa Edema
Sesosa sa mantlha sa 'mele sa mekotla ea mahlo le edema eohle e amanang le periorbital ke ho senyeha ha microcirculation ea lehae., ho eketseha ha capillary permeability e lebisang ho bokellaneng ha metsi a lymphatic. Lipatlisiso li bontša hore peptide ka boeona e fokotsa ho khoneha ha capillary permeability – angiotensin e fetola enzyme (ACE) thibelo e leng mokgoa o le mong wa ketso – ho ntlafatsa phallo ea mali ea lymphatic sebakeng sa heno. Edema ea mahlo le 'mele oa mali’ Ka hona, mekotla e amanang le mahlo le li-circles tse lefifi li fokotsehile.
3. Mokhoa 2: Ho thibela Glycation le ho boloka Collagen
Glycation ke karolo e kholo ho mefuta eohle ea botsofali ba letlalo; lihlahisoa tsa ho qetela tsa glycation (LILEMO) senya botšepehi ba sebopeho sa collagen. Acetyl Tetrapeptide-5 e kenella ts'ebetsong ena ho isa tekanyong e itseng, ho baballa (ho isa ntlheng) elasticity le litšehetso tsohle tse nyane tsa sebopeho tse hlalosang letlalo le tiileng. Didikadikwe tse lefifi, ho ba ponahatso ea pono ea litaba tsa glycation le tsa vascular, le tsona li ntlafalitsoe.
4. Bopaki ba Kliniki le Kopo ea Tlhahiso
Litlamorao tse khahlanong le edema le ho potoloha ha mali li lebisa ho fokotseng kapele ho puffiness. Lintlha tsa kliniki li bonts'a mefuta e mengata ea boreleli le ntlafatso e tiileng sebakeng sa mahlo. Lithuto tsa in vitro li bontšitse a 50% ho fokotseha ha vascular permeability ka bongata ba 1mg / ml. Lithuto tsa boithaopo tsa lithuto tsa batho li bontšitse liphello tse ntle lihlahisoa tsa tlhokomelo ea mahlo tsa nakoana le tse telele tse thibelang botsofali, 'me ka tekanyo e kholo re bona acetyl tetrapeptide-5 e le moemeli oa' nete oa ho thibela botsofali ka mefuta eohle ea eona..
Ka tloaelo le ka katleho ho kopantsoe le li-peptide tse ling, ke motsoako o sebetsang haholo ho thusa letlalo ho shebahala le ho ikutloa le le le le lenyane.
COA
HPLC
MOF
