Peptide CRO Advantage
班级 100 无菌实验室
有机化学专家
提供 mg-kg 级
纯度从粗品到 99%
Multi-modal study routes
Peptide CRO Core Services
Technology development; process mapping.
Design and Synthesis
Customized peptide synthesis
Synthesize peptides of specific sequences (例如. linear peptides, 环肽, modified peptides, ETC。) according to customer requirements.
Modification types
磷酸化, 乙酰化, biotin labeling, fluorescent labeling (异硫氰酸荧光素, Cy series), 聚乙二醇化, ETC.
Special structural peptides
disulfide-bonded cyclic peptides, multimeric peptides, membrane-penetrating peptides (消费者保护计划), glycosylated peptides, ETC.
Peptide library construction
Provide combinatorial peptide libraries (例如. phage display libraries, solid phase synthesis libraries) for high throughput screening.
Process Development
Route design
Chemical synthesis method (solid phase synthesis SPPS, liquid phase synthesis): for short peptides (usually ≤50 氨基酸), need to select protection group strategy, 偶联剂, ETC.
Biosynthesis (recombinant DNA technology): expression of long peptides or complex modified peptides by microorganisms or cells, requires optimization of host selection (例如. 乙. coli, yeast) and culture conditions..
Process optimization
Synthesis/expression optimization: increase yield (例如. 温度, 酸碱度, catalyst concentration).
Purification process: chromatography (reversed-phase HPLC, ion exchange) is key, need to optimize elution conditions.
Impurity control: remove missing peptides, mismatched sequences, oxidation products, ETC. to ensure purity (usually >98%).
交付支持和技术保证
流程的每一步都执行严格的标准
技术
核心保障
- 无菌实验室
- 氮气保护
- 每一步测试
- 有机化学专家
订单
包含的服务
- 高效液相色谱法;多发性硬化症;博士报告
- 免费脱盐、转盐
- 可选的溶出度测试
- 可选的内毒素检测
