Argireline

1.Kedu ihe bụ Argireline

Emepụtara Argireline ka ọ bụrụ ihe nhụsianya dị n'elu karịa nsi botulinum. Agbanyeghị, n'adịghị ka botulinum toxin (“Botox na karama”), nke na-achọ injection subcutaneous, Argireline na-arụ ọrụ site na ngwa ngwa na epidermis, si otú a na-ezere ihe ize ndụ metụtara na subcutaneous injections.

Na isi ya, Argireline na-etinye aka na ya neurotransmitter ntọhapụ site na ikwado na mgbagwoju SNARE (soluble NSF mgbakwunye protein nnabata),nke dị mkpa maka docking acetylcholine nwere vesicles.Site na usoro a, ọ na-akpaghasị nhazi na nkwụsi ike nke mgbagwoju SNARE, si otú a na-egbochi mwepụta neurotransmitter.

Na-ewu na usoro a, karịsịa, ndị ọkà mmụta sayensị mere Argireline na nhazi N-terminus nke protein SNAP-25 . Ọ na-asọmpi na SNAP-25 maka ijikọ ya protein membran jikọtara vesicle (VAMP/synaptobrevin).Teknụzụ peptide a na-akpaghasị nguzobe nke mgbagwoju SNARE, si otú a na-egbochi neuronal exocytosis  [1].

2.Uru Argireline：

Argireline na-enye ezigbo ndidi na enweghị mmegide.Kpọmkwem,uru ndị bụ isi gụnyere:

(1).Mbelata nke nkwekọrịta akwara ihu

Argireline na-ebelata ọdịdị ahịrị okwu(dị ka wrinkles ọkpọiso na ukwu mgbawa) site na igbochi ntọhapụ acetylcholine n'oge exocytosis, nke na-egbochi mkpụkọ akwara. Ọmụmaatụ,Nnyocha ụlọ ọgwụ egosila na 10% ọbara argireline nwere ike ibelata omimi nke wrinkle[2] site 30% emechaa 30 ụbọchị na vivo.

(2).Mmelite na Skin Texture na Smoothness

Ọmụmụ ụlọ ọgwụ egosila na itinye usoro nwere 10% acetyl hexapeptide-8 na akpụkpọ ihu kwa ụbọchị maka 20 ụbọchị nwere ike ibelata akpụkpọ anụ ahụ ma belata transepidermal mmiri ọnwụ (TEWL) [3] .Ọzọkwa,emechaa 4 izu, Nhazi ahụ belatara omimi nke wrinkle site 49% [4] .

(3).Mmelite Ụba na Ọdịmma

Dịkwa mkpa, na a ụlọ ọgwụ ikpe na 26 ndị ọrịa ọnya, E gosipụtara gel Argireline n'elu:

• Mgbanwe akpụkpọ ahụ n'ebe a na-agwọ ọrịa mụbara nke ukwuu.
• Ọkwa hydration belatara ntakịrị
• Mmepụta sebum na mpaghara ọnya ahụ belatara nke ukwuu n'ihe gbasara mpaghara gbara ya gburugburu.

Karịsịa, foto tupu ọgwụgwọ na mgbe emechara, gosipụtara mmụba dị ukwuu na scars nke usoro ịwa ahụ metụtara ọgwụgwọ ọrịa cancer kpatara, mwepụ nke cyst, ma ọ bụ mwepụ ahumachi.

3.Mmechi

Na mkpokọta,Argireline bụ peptide bioactive nke sayensị kwadoro nke nwere usoro omume doro anya. Site n'iṅomi ụzọ omume nke toxin botulinum(“Botox na karama”), ndị mmadụ nwere ike tinye ya n'elu,n'enweghị nsogbu na n'ụzọ dị mma iji jiri nwayọọ mee ka mgbaka akwara kwụsị, na-ebelata ahịrị okwu n'ụzọ dị irè ma melite udidi anụ ahụ [5] .