Tetrapeptide-30 bụ peptide na-egbuke egbuke ọhụrụ.
E sitere na njikarịcha na nṅomi nke usoro a kapịrị ọnụ n'ime ọgwụ mgbochi eke. kathelicidin ezinụlọ, ọ na-anọchi anya ụzọ ọgbara ọhụrụ maka mmepe peptide.
Eke peptides n'onwe ha na-ata ahụhụ site na nkwụsi ike na-adịghị mma na ntinye anụ ahụ na-adịghị mma; Ndị a bụ njedebe ndị bụ isi nke ndị ọkà mmụta sayensị na-etinye aka.
A proline (Pro) ewebata ihe fọdụrụ na N-terminus dịka akụkụ nke usoro a.
A na-ahụ mmụba dị ịrịba ama na nkwụsi ike, A na-abawanye nguzogide proteolytic, a na-akwalitekwa ike nke anụ ahụ nke ọma – A na-echekwa ihe omume ndu nke ọma n'oge niile.
A keukwu, multidimensional netwọk nke ọcha na-wuru – niile nkebi nke melanin A na-ekpuchi mmepụta na mbufe; akpụkpọ ahụ na-egbuke egbuke bụ njedebe ikpeazụ.
Usoro
Pro-Lys-Glu-lys
Nọmba CAS
1036207-61-0
Usoro ihe omimi
C22H41N7O6
Ibu molekụla
499.61
Nnyocha metụtara Tetrapeptide-30
1.Usoro izizi nke ime ihe
Mbelata na ọkwa tyrosinase, mbelata nke homonụ pro-melanocyte α-MSH na mmalite ya POMC, mgbochi nke melanocyte ịgbalite, na n'ikpeazụ mbelata mmepụta nke melanin bụ ụfọdụ n'ime ihe ndị a na-ahụ anya karịa.
Na-eme ihe na mmadụ keratinocytes, hyperpigmentation post-inflammatory na UVB na-akpata pigmenti na-ebelatakwa.
Ntinye aka ozugbo na usoro mbufe (melanocyte na keratinocyte) bụ isi usoro; igbochi ụzọ njem na-aga n'elu bụ akụkụ nke ihe na-eme Tetrapeptide-30 ka ọ bụrụ ihe na-acha ọcha dị irè..
2.Na-ebelata Ọrịa Tyrosinase Ọnụọgụ
Ndị na-egbochi omenala na-arụ ọrụ site na asọmpi saịtị na-arụ ọrụ; Usoro Tetrapeptide-30 nke okwu mkpụrụ ndụ ihe nketa mgbanwe na ikwalite nbibi ya bụ ụdị mgbochi dị mkpa karịa.
Ọcha akpụkpọ (in vitro na ogologo oge) egosila na ọ na-abawanye karịa 10%.
3.Na-egbochi α-MSH/POMC
Dị ka e kwuru n'elu, Nke a bụ ihe mgbochi n'usoro nke mmalite mmalite nke melanocytes.
Mbelata mbufụt na UVB-induced pigmentation bụ usoro nke atọ nke nchebe Tetrapeptide-30 na-enye..
A na-echekwa keratinocytes mmadụ, na ọhụrụ, kwụsie ike, ọnọdụ akpụkpọ ahụ nwere pigmenti ọ bụla bụ ihe a rụpụtara.
Akpụkpọ ahụ ga-enwe nrụgide ruo n'ókè ụfọdụ mgbe niile, mana enwere Tetrapeptide-30, anyị nwere ike ichekwa akpụkpọ anyị nke ọma.
COA
HPLC
MS
