Tetrapeptide-30 is an innovative brightening peptide.
Derived from the optimization and subsequent mimicry of specific sequences within the natural antimicrobial cathelicidin family, it represents a modern approach to peptide development.
Natural peptides themselves suffer from poor stability and poor skin penetration; these are the primary limitations addressed by scientific intervention.
MỘT prolin (chuyên nghiệp) residue at the N-terminus was introduced as part of this process.
Significant improvements in stability are observed, proteolytic resistance is increased, and skin permeability is markedly enhanced – biological activity is well preserved throughout.
A comprehensive, multidimensional network of whitening is constructed – all stages of melanin production and transfer are covered; brighter skin is the end result.
Sự liên tiếp
Pro-Lys-Glu-Lys
Số CAS
1036207-61-0
Công thức phân tử
C22H41N7O6
Trọng lượng phân tử
499.61
Tetrapeptide-30 Related Research
1.Primary Mechanisms of Action
Reductions in tyrosinase levels, lower concentrations of the pro-melanocyte hormone α-MSH and its precursor POMC, inhibition of melanocyte activation, and finally lessened melanin production are some of the more measurable outcomes.
Acting on human keratinocytes, post-inflammatory hyperpigmentation and UVB-induced pigmentation are also reduced.
Direct interference with the transfer process (melanocyte to keratinocyte) is a key mechanism; blocking the transport pathways to the surface is part of what makes Tetrapeptide-30 such an effective whitening agent.
2.Reducing Tyrosinase Số lượng
Traditional inhibitors work by active site competition; Tetrapeptide-30’s method of gene expression modulation and promoting its degradation is a more fundamental form of inhibition.
Skin whiteness (in vitro and long term) has been shown to increase by over 10%.
3.Suppressing α-MSH/POMC
As mentioned above, this is a systematic inhibition of the initial activation of melanocytes.
Reducing inflammation and UVB-induced pigmentation is the third line of defence Tetrapeptide-30 provides.
Human keratinocytes are protected, and a new, stable, evenly pigmented skin state is the achieved outcome.
Skin will always be to some extent stressed, but with Tetrapeptide-30, we can better protect our skin.
COA
HPLC
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