FAQ
Our star product melanotan 2 has a third-party test report, but this is only issued by the Chinese testing organization, we have no way to know whether it has authority in your destination country, other conventional products such as Tirzepatide; Semaglutide; PT141 and other products we provide factory test report.
Yes, each batch of our products is labeled with letters + numbers after production, so that when there is any problem or need for inspection, the production batch can be traced by looking at the letters and numbers on the top of the package.
When you provide third-party proof that the product is found to be non-compliant, we will issue a full refund. However, please let us know if the product has any problems such as moisture absorption during the test period, so that we can accurately trace whether the product has problems in production synthesis or preservation, so that we can optimize our link from production to delivery and prevent the problem from happening again. —— “We do not intentionally reduce purity to make a profit based on business ethics.
We will continue to ship the product free of charge, and you will pay for the logistics costs.
Regular products such as melanotan 2; Tirzepatide; PT141; Retatrutide etc. can be shipped on the 2nd day of payment due to high shipment volume.
Other customized active peptides usually ship in 5-7 days.
Peptides that are more complex to synthesize such as Adamax take 2-3 weeks to ship. However, this is not always the case. If the customized peptide you order happens to be the same as a customer’s order placed a few days before, we will combine the orders and produce your product in advance.
Excluding the production time, the shipping time express: 4-7 days worldwide to reach you.
Air dispatch special line: 18-25 days to arrive (tax inclusive)
We protect our customers’ information by shipping via airmail, which eliminates the need for customers to report and pay customs duties, and which usually involves a carrier contracting an aircraft and taking advantage of an exclusive customs-free channel, the disadvantage of which is that it is too slow, but the advantage of which is that it is reliable.
Solid-phase peptide synthesis is a major breakthrough in the field of peptide synthesis chemistry. Its main feature is the ability to perform the synthesis process continuously without the need to purify intermediate products, thus laying the foundation for the automation of peptide synthesis.
MOL Changes.ltd strictly follows the ISO quality management system for peptide production. Each peptide is assigned a unique identifier, and three HPLC and MS tests are conducted on crude products, purified collection fractions, and final lyophilized products to ensure the accuracy and quality of the products.
The company has expanded its frontline personnel engaged in peptide synthesis to 350 people, with an additional efficient liquid chromatography purification team of over 250 people. The company’s monthly output reaches 10,000 purified peptides. Regular peptides can be delivered within one week, and for the majority of cases, delivery can be completed within two weeks. Quantities range from milligrams to kilograms.
Linear peptide chains are typically synthesized using the Fmoc solid-phase synthesis method, where amino acids are sequentially connected from the C-terminus to the N-terminus.
The purity of a peptide is an important criterion, and the choice of purity depends on the purpose of the experiment. For less sensitive screening experiments, crude or >75% purity is recommended. For immunological studies, >85% purity is advised. For research involving receptor-ligand interactions, biological assays, or cellular studies, >95% purity is recommended. For structural studies, >98% purity is suggested.
The weight of a dry peptide includes not only the peptide itself but also other components such as water, absorbed solvents, coordinating ions, and salts.
Peptide purity is usually determined by HPLC using a standard gradient of 1% per minute. During the synthesis process, the efficiency of crosslinking between amino acids is not always 100%, resulting in a series of impurities with missing amino acids.
When considering peptide synthesis, factors such as peptide length, charge, and hydrophobicity need to be taken into account.
(1) If the peptide contains a high proportion of highly hydrophobic amino acids such as Leu, Val, Ile, Met, Phe, and Trp, the peptide may have difficulty or may be impossible to dissolve in aqueous solutions.
Peptides containing Cys, Met, or Trp are challenging to synthesize and obtain high-purity products. This is mainly due to the instability and susceptibility to oxidation of these functional groups. Special attention is required for the use and storage of these peptides to avoid repeated opening of the vials.
Peptide synthesis differs significantly from primer synthesis, as the inability to synthesize primers is rare, while the inability to synthesize peptides is more common.
Peptides are typically purified using reverse-phase columns (such as C8, C18, etc.) with detection at 214nm.
Generally, peptides used in immunization are around 10-15 amino acids in length.
It is challenging to accurately predict the solubility of a peptide and determine the appropriate solvent.
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