Li-peptide ke barupeluoa ba bohlokoa mesebetsing ea bophelo, 'me liphetoho tse khethehileng tsa tsona le ho ngola li bohlokoa bakeng sa ho ithuta sebopeho le mosebetsi oa tsona. Lilemong tse leshome tse fetileng, mekhoa e entsoe ho ngola glycine ho α-carbon. Leha ho le joalo, mekhoa ena hloka pele ho tshebetso ya glycine, e ke keng ea khonahala bakeng sa temoho e potlakileng ea li-amino acid tsa tlhaho.Phuputsong ena, re tlaleha ts'ebetso e habeli ea α-methylene ea glycine, e khethollang glycine ena ho 19 li-amino acid tse ling.
Melemo ea Setsebi
Khetho e khethehileng, ho sebelisa likarolo tse ikhethang tsa lik'hemik'hale tsa N-terminal glycine ho hlokomela karabelo ea eona e ikhethileng ka ho fetola li-reagents le ho qoba ho kena-kenana le masala a mang a amino acid..
- Bokahohle: E sebetsa ho mefuta e mengata e fapaneng ea li-peptide tse nang le N-terminal glycine, hammoho le lihlopha tse fapaneng tsa phetoho le lidae tsa fluorescent.
- Mefuta e mengata ea lisebelisoa: Fana ka sesebelisoa se matla bakeng sa sebopeho sa peptide le lithuto tsa tšebetso, tlhahlobo ea lithethefatsi, bio-imaging le likarolo tse ling.
Phuputso ena e fana ka mokhoa oa ho khetha li-peptide tsa N-terminal glycine tse sebelisang 1,3-diphenyl 1,3-dione ho fana ka lihlahisoa tsa fluorescent tse thehiloeng ho pyrrole.. E khetha ka thata bakeng sa N-terminal glycine ka lebaka la mochine oa "dual activation".. E fana ka motheo oa theory bakeng sa phetoho e ikhethileng ea N-glycine-based fluorescence le mokhoa oa tlhahlobo ea botsitso bakeng sa ho tsebahatsa ka potlako li-peptide tse nang le N-terminal glycine..
