Tetrapeptide-30

Tetrapeptide-30 Related Research

1.Primary Mechanisms of Action

Reductions in tyrosinase levels, lower concentrations of the pro-melanocyte hormone α-MSH and its precursor POMC, inhibition of melanocyte activation, and finally lessened melanin production are some of the more measurable outcomes.

Acting on human keratinocytes, post-inflammatory hyperpigmentation and UVB-induced pigmentation are also reduced.

Direct interference with the transfer process (melanocyte to keratinocyte) is a key mechanism; blocking the transport pathways to the surface is part of what makes Tetrapeptide-30 such an effective whitening agent.

2.Reducing Tyrosinase Quantity

Traditional inhibitors work by active site competition; Tetrapeptide-30’s method of gene expression modulation and promoting its degradation is a more fundamental form of inhibition.

Skin whiteness (in vitro and long term) has been shown to increase by over 10%.

3.Suppressing α-MSH/POMC

As mentioned above, this is a systematic inhibition of the initial activation of melanocytes.

Reducing inflammation and UVB-induced pigmentation is the third line of defence Tetrapeptide-30 provides.

Human keratinocytes are protected, and a new, stable, evenly pigmented skin state is the achieved outcome.

Skin will always be to some extent stressed, but with Tetrapeptide-30, we can better protect our skin.